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    Arf1 ADP-ribosylation factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 11840, updated on 5-Sep-2021

    Summary

    Official Symbol
    Arf1provided by MGI
    Official Full Name
    ADP-ribosylation factor 1provided by MGI
    Primary source
    MGI:MGI:99431
    See related
    Ensembl:ENSMUSG00000048076
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in large intestine adult (RPKM 273.0), duodenum adult (RPKM 269.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Arf1 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59102238..59119093, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59211412..59228267, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (59024914..59041769, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2310033P09 gene Neighboring gene mitochondrial ribosomal protein L55 Neighboring gene wingless-type MMTV integration site family, member 3A Neighboring gene wingless-type MMTV integration site family, member 9A Neighboring gene predicted gene, 51865

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTP binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables magnesium ion binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipase D activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to transport vesicle transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in actin filament organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dendritic spine organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in long-term synaptic depression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lysosomal membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cleavage furrow ingression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of ER to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of calcium ion-dependent exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of dendritic spine development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of late endosome to lysosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of sodium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in postsynaptic actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of Arp2/3 complex-mediated actin nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of phospholipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle budding ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in very-low-density lipoprotein particle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within vesicle-mediated transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with COPI-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell leading edge ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endomembrane system IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein-containing complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcomere IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130408.1NP_001123880.1  ADP-ribosylation factor 1

      See identical proteins and their annotated locations for NP_001123880.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AK148458, AK152479
      Consensus CDS
      CCDS24765.1
      UniProtKB/Swiss-Prot
      P84078
      Related
      ENSMUSP00000126120.2, ENSMUST00000163300.8
      Conserved Domains (1) summary
      smart00177
      Location:5179
      ARF; ARF-like small GTPases; ARF, ADP-ribosylation factor
    2. NM_007476.3NP_031502.1  ADP-ribosylation factor 1

      See identical proteins and their annotated locations for NP_031502.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1.
      Source sequence(s)
      AK148458, CN705066
      Consensus CDS
      CCDS24765.1
      UniProtKB/Swiss-Prot
      P84078
      Related
      ENSMUSP00000079905.7, ENSMUST00000061242.8
      Conserved Domains (1) summary
      smart00177
      Location:5179
      ARF; ARF-like small GTPases; ARF, ADP-ribosylation factor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      59102238..59119093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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