Format

Send to:

Choose Destination
    • Showing Current items.

    Ap1s1 adaptor protein complex AP-1, sigma 1 [ Mus musculus (house mouse) ]

    Gene ID: 11769, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ap1s1provided by MGI
    Official Full Name
    adaptor protein complex AP-1, sigma 1provided by MGI
    Primary source
    MGI:MGI:1098244
    See related
    Ensembl:ENSMUSG00000004849
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AP19
    Expression
    Ubiquitous expression in cortex adult (RPKM 34.6), frontal lobe adult (RPKM 34.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ap1s1 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (137034993..137046060, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (137510864..137521930, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 26989 Neighboring gene VGF nerve growth factor inducible Neighboring gene serine (or cysteine) peptidase inhibitor, clade E, member 1 Neighboring gene tripartite motif-containing 56

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein transporter activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    intracellular protein transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    retrograde transport, endosome to Golgi IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    AP-1 adaptor complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane coat IEA
    Inferred from Electronic Annotation
    more info
     
    terminal bouton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trans-Golgi network NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit sigma-1A
    Names
    HA1 19 kDa subunit
    adapter-related protein complex 1 sigma-1A subunit
    adapter-related protein complex 1 subunit sigma-1A
    adaptor protein complex AP-1 sigma-1A subunit
    adaptor protein complex AP-1 subunit sigma-1A
    adaptor-related protein complex 1 subunit sigma-1A
    adaptor-related protein complex AP-1, sigma 1
    clathrin assembly protein complex 1 sigma-1A small chain
    clathrin coat assembly protein AP19
    golgi adaptor HA1/AP1 adaptin sigma-1A subunit
    sigma 1a subunit of AP-1 clathrin
    sigma-adaptin 1A
    sigma1A-adaptin

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007457.3NP_031483.1  AP-1 complex subunit sigma-1A

      See identical proteins and their annotated locations for NP_031483.1

      Status: VALIDATED

      Source sequence(s)
      BC052692, BY253222
      Consensus CDS
      CCDS39330.1
      UniProtKB/Swiss-Prot
      P61967
      Related
      ENSMUSP00000106709.1, ENSMUST00000111080.7
      Conserved Domains (1) summary
      pfam01217
      Location:1142
      Clat_adaptor_s; Clathrin adaptor complex small chain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      137034993..137046060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504348.3XP_006504411.1  AP-1 complex subunit sigma-1A isoform X1

      Conserved Domains (1) summary
      pfam01217
      Location:20160
      Clat_adaptor_s; Clathrin adaptor complex small chain
    Support Center