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    Ap1s1 adaptor protein complex AP-1, sigma 1 [ Mus musculus (house mouse) ]

    Gene ID: 11769, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ap1s1provided by MGI
    Official Full Name
    adaptor protein complex AP-1, sigma 1provided by MGI
    Primary source
    MGI:MGI:1098244
    See related
    Ensembl:ENSMUSG00000004849
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AP; AP19
    Expression
    Ubiquitous expression in cortex adult (RPKM 34.6), frontal lobe adult (RPKM 34.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ap1s1 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137063847..137074962, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137034993..137046108, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (137510864..137521930, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26989 Neighboring gene VGF nerve growth factor inducible Neighboring gene serine (or cysteine) peptidase inhibitor, clade E, member 1 Neighboring gene tripartite motif-containing 56

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within retrograde transport, endosome to Golgi IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of AP-1 adaptor complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
     
    located_in terminal bouton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit sigma-1A
    Names
    HA1 19 kDa subunit
    adapter-related protein complex 1 sigma-1A subunit
    adapter-related protein complex 1 subunit sigma-1A
    adaptor protein complex AP-1 sigma-1A subunit
    adaptor protein complex AP-1 subunit sigma-1A
    adaptor-related protein complex 1 subunit sigma-1A
    adaptor-related protein complex AP-1, sigma 1
    clathrin assembly protein complex 1 sigma-1A small chain
    clathrin coat assembly protein AP19
    golgi adaptor HA1/AP1 adaptin sigma-1A subunit
    sigma 1a subunit of AP-1 clathrin
    sigma-adaptin 1A
    sigma1A-adaptin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007457.3NP_031483.1  AP-1 complex subunit sigma-1A

      See identical proteins and their annotated locations for NP_031483.1

      Status: VALIDATED

      Source sequence(s)
      BC052692, BY253222
      Consensus CDS
      CCDS39330.1
      UniProtKB/Swiss-Prot
      P61967
      Related
      ENSMUSP00000106709.2, ENSMUST00000111080.8
      Conserved Domains (1) summary
      cd14831
      Location:3145
      AP1_sigma; AP-1 complex subunit sigma

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      137063847..137074962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164745.1XP_036020638.1  AP-1 complex subunit sigma-1A isoform X1

      Related
      ENSMUSP00000115941.2, ENSMUST00000150603.8
      Conserved Domains (1) summary
      cd14831
      Location:36178
      AP1_sigma; AP-1 complex subunit sigma
    2. XM_006504348.5XP_006504411.1  AP-1 complex subunit sigma-1A isoform X2

      Conserved Domains (1) summary
      cd14831
      Location:21163
      AP1_sigma; AP-1 complex subunit sigma
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