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    Ap1m2 adaptor protein complex AP-1, mu 2 subunit [ Mus musculus (house mouse) ]

    Gene ID: 11768, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ap1m2provided by MGI
    Official Full Name
    adaptor protein complex AP-1, mu 2 subunitprovided by MGI
    Primary source
    MGI:MGI:1336974
    See related
    Ensembl:ENSMUSG00000003309
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mu1B; [m]1B; D9Ertd818e
    Expression
    Biased expression in large intestine adult (RPKM 27.8), colon adult (RPKM 22.4) and 13 other tissues See more
    Orthologs

    Genomic context

    See Ap1m2 in Genome Data Viewer
    Location:
    9 A3; 9 7.76 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (21294615..21312349, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21099901..21116777, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene autophagy related 4D, cysteine peptidase Neighboring gene KRI1 homolog Neighboring gene cyclin dependent kinase inhibitor 2D Neighboring gene predicted gene, 39302 Neighboring gene solute carrier family 44, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    intracellular protein transport TAS
    Traceable Author Statement
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    trans-Golgi network TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit mu-2
    Names
    AP-mu chain family member mu1B
    adaptor protein complex AP-1 subunit mu-2
    adaptor-related protein complex 1 mu-2 subunit
    adaptor-related protein complex 1 subunit mu-2
    adaptor-related protein complex AP-1, mu 2 subunit
    clathrin assembly protein complex 1 medium chain 2
    clathrin assembly protein complex 1 mu-2 medium chain 2
    golgi adaptor HA1/AP1 adaptin mu-2 subunit
    mu-adaptin 2
    mu1B-adaptin

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110300.1NP_001103770.1  AP-1 complex subunit mu-2 isoform 1

      See identical proteins and their annotated locations for NP_001103770.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
      Source sequence(s)
      AK010478, AK082674, CJ078558
      Consensus CDS
      CCDS52734.1
      UniProtKB/Swiss-Prot
      Q9WVP1
      UniProtKB/TrEMBL
      A0A0R4J1L4
      Related
      ENSMUSP00000111093.3, ENSMUST00000115433.10
      Conserved Domains (1) summary
      cl10970
      Location:154423
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    2. NM_009678.2NP_033808.2  AP-1 complex subunit mu-2 isoform 2

      See identical proteins and their annotated locations for NP_033808.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different splice site in the CDS, compared to variant 1. The resulting protein (isoform 2) is shorter by 2 aa when it is compared to isoform 1.
      Source sequence(s)
      AK010478, AK082674, CJ078558
      Consensus CDS
      CCDS22902.1
      UniProtKB/Swiss-Prot
      Q9WVP1
      UniProtKB/TrEMBL
      A0A0R4IZX6
      Related
      ENSMUSP00000003397.7, ENSMUST00000003397.8
      Conserved Domains (1) summary
      cl10970
      Location:154421
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      21294615..21312349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509950.3XP_006510013.1  AP-1 complex subunit mu-2 isoform X2

      See identical proteins and their annotated locations for XP_006510013.1

      Conserved Domains (1) summary
      cl10970
      Location:119386
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    2. XM_006509949.3XP_006510012.1  AP-1 complex subunit mu-2 isoform X1

      Conserved Domains (1) summary
      cl10970
      Location:119388
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
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