Format

Send to:

Choose Destination
    • Showing Current items.

    Ap1g1 adaptor protein complex AP-1, gamma 1 subunit [ Mus musculus (house mouse) ]

    Gene ID: 11765, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ap1g1provided by MGI
    Official Full Name
    adaptor protein complex AP-1, gamma 1 subunitprovided by MGI
    Primary source
    MGI:MGI:101919
    See related
    Ensembl:ENSMUSG00000031731
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adt; Adtg; AA409002; AU041323; AW551707; D8Ertd374; D8Ertd374e
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 17.8), CNS E18 (RPKM 17.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ap1g1 in Genome Data Viewer
    Location:
    8 D3; 8 57.26 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (110505215..110590842)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (109778583..109864210)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (112302540..112384835)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ataxin 1-like Neighboring gene predicted gene, 51550 Neighboring gene La ribonucleoprotein domain family, member 1B pseudogene Neighboring gene predicted gene, 17344 Neighboring gene small nucleolar RNA, C/D box 71 Neighboring gene predicted gene, 25321 Neighboring gene PH domain and leucine rich repeat protein phosphatase 2 Neighboring gene MARVEL (membrane-associating) domain containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cargo adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables clathrin adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables kinesin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of AP-1 adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit gamma-1
    Names
    adapter-related protein complex 1 subunit gamma-1
    adaptor protein complex AP-1 subunit gamma-1
    adaptor-related protein complex 1 subunit gamma-1
    clathrin assembly protein complex 1 gamma-1 large chain
    gamma-adaptin
    gamma1-adaptin
    golgi adaptor HA1/AP1 adaptin subunit gamma-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301211.1NP_001288140.1  AP-1 complex subunit gamma-1 isoform 2

      See identical proteins and their annotated locations for NP_001288140.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC122807, BU755831, BY738987, X54424
      Consensus CDS
      CCDS80929.1
      UniProtKB/Swiss-Prot
      P22892
      Related
      ENSMUSP00000034171.9, ENSMUST00000034171.9
      Conserved Domains (4) summary
      smart00809
      Location:709817
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam05109
      Location:590702
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00044
      Location:142163
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:23574
      Adaptin_N; Adaptin N terminal region
    2. NM_009677.6NP_033807.2  AP-1 complex subunit gamma-1 isoform 1

      See identical proteins and their annotated locations for NP_033807.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC122807, AK036387, BU755831, BY738987
      Consensus CDS
      CCDS40475.1
      UniProtKB/TrEMBL
      Q8CBB7
      Related
      ENSMUSP00000090844.7, ENSMUST00000093157.13
      Conserved Domains (4) summary
      smart00809
      Location:712820
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam05109
      Location:593705
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00044
      Location:142163
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:23577
      Adaptin_N; Adaptin N terminal region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      110505215..110590842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center