Format

Send to:

Choose Destination
    • Showing Current items.

    Ap1g1 adaptor protein complex AP-1, gamma 1 subunit [ Mus musculus (house mouse) ]

    Gene ID: 11765, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ap1g1provided by MGI
    Official Full Name
    adaptor protein complex AP-1, gamma 1 subunitprovided by MGI
    Primary source
    MGI:MGI:101919
    See related
    Ensembl:ENSMUSG00000031731
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adtg; AA409002; AU041323; AW551707; D8Ertd374e
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 17.8), CNS E18 (RPKM 17.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ap1g1 in Genome Data Viewer
    Location:
    8 D3; 8 57.26 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (109778583..109864210)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (112302540..112384835)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene ataxin 1-like Neighboring gene La ribonucleoprotein domain family, member 1B pseudogene Neighboring gene small nucleolar RNA, C/D box 71 Neighboring gene PH domain and leucine rich repeat protein phosphatase 2 Neighboring gene MARVEL (membrane-associating) domain containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Rab GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    collagen binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinesin binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Golgi to lysosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    endosome to melanosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport TAS
    Traceable Author Statement
    more info
    PubMed 
    microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of natural killer cell degranulation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    AP-1 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cell ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane coat IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trans-Golgi network TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit gamma-1
    Names
    adapter-related protein complex 1 subunit gamma-1
    adaptor protein complex AP-1 subunit gamma-1
    adaptor-related protein complex 1 subunit gamma-1
    clathrin assembly protein complex 1 gamma-1 large chain
    gamma-adaptin
    gamma1-adaptin
    golgi adaptor HA1/AP1 adaptin subunit gamma-1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301211.1NP_001288140.1  AP-1 complex subunit gamma-1 isoform 2

      See identical proteins and their annotated locations for NP_001288140.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC122807, BU755831, BY738987, X54424
      Consensus CDS
      CCDS80929.1
      UniProtKB/Swiss-Prot
      P22892
      Related
      ENSMUSP00000034171.8, ENSMUST00000034171.8
      Conserved Domains (4) summary
      smart00809
      Location:709817
      Alpha_adaptinC2; Adaptin C-terminal domain
      sd00044
      Location:142163
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:23574
      Adaptin_N; Adaptin N terminal region
      cl25496
      Location:590702
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    2. NM_009677.6NP_033807.2  AP-1 complex subunit gamma-1 isoform 1

      See identical proteins and their annotated locations for NP_033807.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC122807, AK036387, BU755831, BY738987
      Consensus CDS
      CCDS40475.1
      UniProtKB/TrEMBL
      Q8CBB7
      Related
      ENSMUSP00000090844.6, ENSMUST00000093157.12
      Conserved Domains (4) summary
      smart00809
      Location:712820
      Alpha_adaptinC2; Adaptin C-terminal domain
      sd00044
      Location:142163
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:23577
      Adaptin_N; Adaptin N terminal region
      cl25496
      Location:593705
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      109778583..109864210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center