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    Amd1 S-adenosylmethionine decarboxylase 1 [ Mus musculus (house mouse) ]

    Gene ID: 11702, updated on 31-Jan-2019

    Summary

    Official Symbol
    Amd1provided by MGI
    Official Full Name
    S-adenosylmethionine decarboxylase 1provided by MGI
    Primary source
    MGI:MGI:88004
    See related
    Ensembl:ENSMUSG00000075232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Amd-1; SAMDC; SAMDC 1; AdoMetDC; adoMetDC1
    Expression
    Broad expression in bladder adult (RPKM 38.2), liver E14 (RPKM 34.2) and 24 other tissues See more
    Orthologs

    Genomic context

    See Amd1 in Genome Data Viewer
    Location:
    10 B1; 10 21.85 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (40287458..40302188, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (40007265..40021992, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene general transcription factor IIIC, polypeptide 6, alpha Neighboring gene U3A small nuclear RNA Neighboring gene predicted gene 8948 Neighboring gene cyclin-dependent kinase 19 Neighboring gene high mobility group box 1-like pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC91044, MGC102468

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    adenosylmethionine decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    adenosylmethionine decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    adenosylmethionine decarboxylase activity ISO
    Inferred from Sequence Orthology
    more info
     
    carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    putrescine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    putrescine binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    polyamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    spermidine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spermidine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spermine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spermine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    S-adenosylmethionine decarboxylase proenzyme 1
    Names
    adoMetDC 1
    NP_033795.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009665.5NP_033795.1  S-adenosylmethionine decarboxylase proenzyme 1

      See identical proteins and their annotated locations for NP_033795.1

      Status: VALIDATED

      Source sequence(s)
      AC142273, AK146840
      Consensus CDS
      CCDS48544.1
      UniProtKB/Swiss-Prot
      P0DMN7
      Related
      ENSMUSP00000097528.4, ENSMUST00000099945.5
      Conserved Domains (1) summary
      pfam01536
      Location:4325
      SAM_decarbox; Adenosylmethionine decarboxylase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      40287458..40302188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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