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    Alppl2 alkaline phosphatase, placental-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 11650, updated on 31-Jan-2019

    Summary

    Official Symbol
    Alppl2provided by MGI
    Official Full Name
    alkaline phosphatase, placental-like 2provided by MGI
    Primary source
    MGI:MGI:108009
    See related
    Ensembl:ENSMUSG00000026246
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EAP; Akp5; Alpg; C77216; D1Ertd816e
    Expression
    Biased expression in genital fat pad adult (RPKM 7.5), testis adult (RPKM 2.2) and 3 other tissues See more

    Genomic context

    See Alppl2 in Genome Data Viewer
    Location:
    1 C5; 1 44.05 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (87086690..87095934, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (88983265..88986503, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene alkaline phosphatase pseudogene 1 Neighboring gene predicted gene, 41910 Neighboring gene predicted gene 29371 Neighboring gene alkaline phosphatase, intestinal Neighboring gene alkaline phosphatase 3, intestine, not Mn requiring

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    alkaline phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    alkaline phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    anchored component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    myofibril IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    alkaline phosphatase, germ cell type; alkaline phosphatase, placental-like
    Names
    alkaline phosphatase 5
    embryonic alkaline phosphatase
    embryonic-type alkaline phosphatase
    NP_031459.3
    XP_006529145.1
    XP_011246206.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007433.3NP_031459.3  alkaline phosphatase, germ cell type precursor

      See identical proteins and their annotated locations for NP_031459.3

      Status: VALIDATED

      Source sequence(s)
      AK145571, BB727113, BC052874, CN717647
      Consensus CDS
      CCDS15126.1
      UniProtKB/Swiss-Prot
      P24823
      UniProtKB/TrEMBL
      Q7TPW4
      Related
      ENSMUSP00000027455.6, ENSMUST00000027455.12
      Conserved Domains (2) summary
      PRK10518
      Location:16473
      PRK10518; alkaline phosphatase; Provisional
      pfam00245
      Location:51486
      Alk_phosphatase; Alkaline phosphatase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      87086690..87095934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529082.3XP_006529145.1  alkaline phosphatase, placental-like isoform X1

      See identical proteins and their annotated locations for XP_006529145.1

      UniProtKB/Swiss-Prot
      P24823
      Conserved Domains (2) summary
      PRK10518
      Location:16473
      PRK10518; alkaline phosphatase; Provisional
      pfam00245
      Location:51486
      Alk_phosphatase; Alkaline phosphatase
    2. XM_011247904.2XP_011246206.1  alkaline phosphatase, placental-like isoform X1

      See identical proteins and their annotated locations for XP_011246206.1

      UniProtKB/Swiss-Prot
      P24823
      Conserved Domains (2) summary
      PRK10518
      Location:16473
      PRK10518; alkaline phosphatase; Provisional
      pfam00245
      Location:51486
      Alk_phosphatase; Alkaline phosphatase
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