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    Dcun1d1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 114893, updated on 18-Sep-2018

    Summary

    Official Symbol
    Dcun1d1provided by MGI
    Official Full Name
    DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:2150386
    See related
    Ensembl:ENSMUSG00000027708 Vega:OTTMUSG00000028173
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rp42; Tes3; SCCRO; pTes3
    Expression
    Broad expression in testis adult (RPKM 11.9), liver E14 (RPKM 6.9) and 21 other tissues See more
    Orthologs

    Genomic context

    See Dcun1d1 in Genome Data Viewer
    Location:
    3; 3 B
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (35892105..35937440, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (35791903..35828996, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene chaperonin containing Tcp1, subunit 8 (theta) pseudogene Neighboring gene predicted gene 15952 Neighboring gene methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) Neighboring gene methylcrotonoyl-Coenzyme A carboxylase 1 (alpha), opposite strand Neighboring gene coiled-coil domain containing 144B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cullin family protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-like protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of protein neddylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein neddylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DCN1-like protein 1
    Names
    DCUN1 domain-containing protein 1
    defective in cullin neddylation protein 1-like protein 1
    testis derived transcript 3
    testis-specific protein 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205361.1NP_001192290.1  DCN1-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001192290.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC116677, AK008657
      Consensus CDS
      CCDS57207.1
      UniProtKB/Swiss-Prot
      Q9QZ73
      Related
      ENSMUSP00000103817.5, OTTMUSP00000035493, ENSMUST00000108182.9, OTTMUST00000069785
      Conserved Domains (2) summary
      cd14411
      Location:151
      UBA_DCNL1; UBA-like domain found in DCN1-like protein 1 (DCNL1) and similar proteins
      pfam03556
      Location:136246
      Cullin_binding; Cullin binding
    2. NM_001205362.1NP_001192291.1  DCN1-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001192291.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform (2).
      Source sequence(s)
      AC116677
      Consensus CDS
      CCDS17306.1
      UniProtKB/TrEMBL
      Q3UT23
      Related
      ENSMUSP00000137324.1, ENSMUST00000178098.7
      Conserved Domains (2) summary
      pfam03556
      Location:121231
      Cullin_binding; Cullin binding
      cl21463
      Location:136
      UBA_like_SF; UBA domain-like superfamily
    3. NM_033623.6NP_296372.3  DCN1-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_296372.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform (2).
      Source sequence(s)
      AC116677, AK139845
      Consensus CDS
      CCDS17306.1
      UniProtKB/TrEMBL
      Q3UT23
      Related
      ENSMUSP00000143243.1, OTTMUSP00000035494, ENSMUST00000198389.4, OTTMUST00000069786
      Conserved Domains (2) summary
      pfam03556
      Location:121231
      Cullin_binding; Cullin binding
      cl21463
      Location:136
      UBA_like_SF; UBA domain-like superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      35892105..35937440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535374.2XP_006535437.1  DCN1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006535437.1

      UniProtKB/TrEMBL
      Q3UT23
      Related
      ENSMUSP00000115420.3, OTTMUSP00000035495, ENSMUST00000148465.7, OTTMUST00000069787
      Conserved Domains (2) summary
      pfam03556
      Location:121231
      Cullin_binding; Cullin binding
      cl21463
      Location:136
      UBA_like_SF; UBA domain-like superfamily
    2. XM_006535375.3XP_006535438.1  DCN1-like protein 1 isoform X2

      Conserved Domains (2) summary
      pfam03556
      Location:136173
      Cullin_binding; Cullin binding
      cl21463
      Location:151
      UBA_like_SF; UBA domain-like superfamily
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