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    MISP3 MISP family member 3 [ Homo sapiens (human) ]

    Gene ID: 113230, updated on 17-Jun-2024

    Summary

    Official Symbol
    MISP3provided by HGNC
    Official Full Name
    MISP family member 3provided by HGNC
    Primary source
    HGNC:HGNC:26963
    See related
    Ensembl:ENSG00000141854 AllianceGenome:HGNC:26963
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in kidney (RPKM 7.9), colon (RPKM 7.2) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See MISP3 in Genome Data Viewer
    Location:
    19p13.12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (14072786..14075062)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (14199078..14201354)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (14183598..14185874)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:14166912-14167412 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:14167413-14167913 Neighboring gene paralemmin 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:14172829-14173383 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10226 Neighboring gene eukaryotic translation elongation factor 1 delta pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10227 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:14184754-14185274 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:14185989-14186224 Neighboring gene microRNA 1199 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14153 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14154 Neighboring gene chromosome 19 open reading frame 67 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:14199415-14199924 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10228 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10229 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10230 Neighboring gene sterile alpha motif domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein MISP3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291291.2NP_001278220.1  uncharacterized protein MISP3 isoform 1

      See identical proteins and their annotated locations for NP_001278220.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the protein.
      Source sequence(s)
      AC022098, BC011002
      Consensus CDS
      CCDS77246.1
      UniProtKB/Swiss-Prot
      Q96FF7
      Related
      ENSP00000465157.1, ENST00000587086.3
      Conserved Domains (1) summary
      pfam15304
      Location:37208
      AKAP2_C; A-kinase anchor protein 2 C-terminus
    2. NM_001393577.1NP_001380506.1  uncharacterized protein MISP3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC022098

    RNA

    1. NR_111941.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site at an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC022098

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      14072786..14075062
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_021160022.1 Reference GRCh38.p14 PATCHES

      Range
      284627..286903
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      14199078..14201354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)