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    Dek DEK oncogene (DNA binding) [ Mus musculus (house mouse) ]

    Gene ID: 110052, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dekprovided by MGI
    Official Full Name
    DEK oncogene (DNA binding)provided by MGI
    Primary source
    MGI:MGI:1926209
    See related
    Ensembl:ENSMUSG00000021377
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D13H6S231E; 1810019E15Rik
    Expression
    Biased expression in liver E14 (RPKM 94.0), liver E14.5 (RPKM 74.8) and 12 other tissues See more
    Orthologs

    Genomic context

    See Dek in Genome Data Viewer
    Location:
    13 A5; 13 24.5 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (47084767..47106227, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (47180136..47201589, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene NHL repeat containing 1 Neighboring gene NLR family, pyrin domain containing 4B pseudogene Neighboring gene thiopurine methyltransferase Neighboring gene lysine (K)-specific demethylase 1B Neighboring gene predicted gene, 40935 Neighboring gene ring finger protein 144B Neighboring gene RIKEN cDNA A930002C04 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of double-strand break repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of double-strand break repair ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of double-strand break repair via nonhomologous end joining IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    contractile fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025900.2NP_080176.2  protein DEK

      See identical proteins and their annotated locations for NP_080176.2

      Status: VALIDATED

      Source sequence(s)
      AK033451, AK141790, AV449751, BU920290, BY429959
      Consensus CDS
      CCDS26490.1
      UniProtKB/Swiss-Prot
      Q7TNV0
      UniProtKB/TrEMBL
      Q3UR53
      Related
      ENSMUSP00000021807.6, ENSMUST00000021807.12
      Conserved Domains (2) summary
      smart00513
      Location:153187
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam08766
      Location:327379
      DEK_C; DEK C terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      47084767..47106227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_382230.2 RNA Sequence

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