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    ADIRF adipogenesis regulatory factor [ Homo sapiens (human) ]

    Gene ID: 10974, updated on 25-Nov-2021

    Summary

    Official Symbol
    ADIRFprovided by HGNC
    Official Full Name
    adipogenesis regulatory factorprovided by HGNC
    Primary source
    HGNC:HGNC:24043
    See related
    Ensembl:ENSG00000148671
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AFRO; APM2; apM-2; C10orf116
    Summary
    APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in fat (RPKM 830.0), prostate (RPKM 218.1) and 10 other tissues See more
    Orthologs
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    Genomic context

    See ADIRF in Genome Data Viewer
    Location:
    10q23.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (86968482..86970915)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (88728239..88730672)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene multimerin 2 Neighboring gene Sharpr-MPRA regulatory region 565 Neighboring gene synuclein gamma Neighboring gene ADIRF antisense RNA 1 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 Neighboring gene BMS1 pseudogene 3 Neighboring gene family with sequence similarity 25 member A

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in extracellular exosome HDA PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    adipogenesis regulatory factor
    Names
    adipogenesis factor rich in obesity
    adipose most abundant gene transcript 2 protein
    adipose specific 2
    adipose-specific protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_006829.3NP_006820.1  adipogenesis regulatory factor

      See identical proteins and their annotated locations for NP_006820.1

      Status: VALIDATED

      Source sequence(s)
      AI401530, AL136982, BM789611, BM850559, CD722742
      Consensus CDS
      CCDS7381.1
      UniProtKB/Swiss-Prot
      Q15847
      UniProtKB/TrEMBL
      Q5TBU5
      Related
      ENSP00000361083.3, ENST00000372013.8

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

      Range
      86968482..86970915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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