Format

Send to:

Choose Destination
    • Showing Current items.

    Lmo1 LIM domain only 1 [ Mus musculus (house mouse) ]

    Gene ID: 109594, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lmo1provided by MGI
    Official Full Name
    LIM domain only 1provided by MGI
    Primary source
    MGI:MGI:102812
    See related
    Ensembl:ENSMUSG00000036111
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rbt; Rbtn; Ttg1; Rbtn1; Rbtn-1
    Expression
    Broad expression in bladder adult (RPKM 28.1), whole brain E14.5 (RPKM 23.1) and 16 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lmo1 in Genome Data Viewer
    Location:
    7 E3; 7 57.21 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (108737772..108774414, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (109138565..109175207, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (116282086..116313822, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene tubby bipartite transcription factor Neighboring gene RIC3 acetylcholine receptor chaperone Neighboring gene predicted gene, 25450 Neighboring gene predicted gene 44781 Neighboring gene predicted gene, 32563 Neighboring gene predicted gene, 51463

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    rhombotin-1
    Names
    LIM domain only protein 1
    LIM only 1
    LMO-1
    T-cell translocation protein 1
    cysteine-rich protein TTG-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001302205.1NP_001289134.1  rhombotin-1 isoform 2

      See identical proteins and their annotated locations for NP_001289134.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an upstream alternate 5'-terminal exon which reflects use of an alternate promoter supported by epigenetic data, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AV250089, AW494084, BC053074
      Consensus CDS
      CCDS85378.1
      UniProtKB/Swiss-Prot
      Q924W9
      UniProtKB/TrEMBL
      A0A140LIB4
      Related
      ENSMUSP00000146752.2, ENSMUST00000207178.2
      Conserved Domains (2) summary
      cd09388
      Location:2377
      LIM1_LMO1_LMO3; The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
      cd09389
      Location:87141
      LIM2_LMO1_LMO3; The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
    2. NM_001302206.1NP_001289135.1  rhombotin-1 isoform 3

      See identical proteins and their annotated locations for NP_001289135.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AA050915, AC147221, AV250089, BC053074
      Consensus CDS
      CCDS85377.1
      UniProtKB/Swiss-Prot
      Q924W9
      UniProtKB/TrEMBL
      A0A140LHX4
      Related
      ENSMUSP00000146588.2, ENSMUST00000208136.2
      Conserved Domains (2) summary
      cd09388
      Location:1367
      LIM1_LMO1_LMO3; The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
      cd09389
      Location:77131
      LIM2_LMO1_LMO3; The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
    3. NM_001382564.1NP_001369493.1  rhombotin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC147221
      Conserved Domains (2) summary
      cd09388
      Location:2478
      LIM1_LMO1_LMO3; The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
      cd09389
      Location:88142
      LIM2_LMO1_LMO3; The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
    4. NM_057173.3NP_476514.1  rhombotin-1 isoform 1

      See identical proteins and their annotated locations for NP_476514.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1)
      Source sequence(s)
      AV250089, BC053074, DV662082
      Consensus CDS
      CCDS40080.1
      UniProtKB/Swiss-Prot
      Q924W9
      UniProtKB/TrEMBL
      Q3UZX1
      Related
      ENSMUSP00000037079.8, ENSMUST00000036992.9
      Conserved Domains (2) summary
      cd09388
      Location:2478
      LIM1_LMO1_LMO3; The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)
      cd09389
      Location:88142
      LIM2_LMO1_LMO3; The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      108737772..108774414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center