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    C11orf58 chromosome 11 open reading frame 58 [ Homo sapiens (human) ]

    Gene ID: 10944, updated on 5-May-2024

    Summary

    Official Symbol
    C11orf58provided by HGNC
    Official Full Name
    chromosome 11 open reading frame 58provided by HGNC
    Primary source
    HGNC:HGNC:16990
    See related
    Ensembl:ENSG00000110696 MIM:619625; AllianceGenome:HGNC:16990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SMAP; IMAGE145052
    Expression
    Ubiquitous expression in thyroid (RPKM 25.7), endometrium (RPKM 22.9) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See C11orf58 in Genome Data Viewer
    Location:
    11p15.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (16738647..16758340)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (16836026..16855719)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (16760194..16779887)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene SRY-box transcription factor 6 Neighboring gene MPRA-validated peak1218 silencer Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:16628669-16629170 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:16629171-16629670 Neighboring gene uncharacterized LOC105376571 Neighboring gene RNA, 7SL, cytoplasmic 188, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16691079-16691580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16691581-16692082 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16699888-16700416 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16700417-16700944 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:16730412-16730912 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:16730913-16731413 Neighboring gene MPRA-validated peak1219 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16800297-16801020 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:16801021-16801743 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16802139-16802833 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16802834-16803527 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16803848-16804825 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16812092-16812592 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16812593-16813093 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:16823697-16824896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16836605-16837105 Neighboring gene pleckstrin homology domain containing A7 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:16875052-16875264 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4481 Neighboring gene VISTA enhancer hs2096 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:16918881-16919566 Neighboring gene RN7SK pseudogene 90 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16946213-16946824 Neighboring gene small nucleolar RNA, C/D box 147

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC117265, DKFZp686N0232

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014267.6NP_055082.1  small acidic protein

      See identical proteins and their annotated locations for NP_055082.1

      Status: VALIDATED

      Source sequence(s)
      AC026639
      Consensus CDS
      CCDS7822.1
      UniProtKB/Swiss-Prot
      B2RD28, O00193
      Related
      ENSP00000228136.4, ENST00000228136.9
      Conserved Domains (1) summary
      pfam15477
      Location:27103
      SMAP; Small acidic protein family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      16738647..16758340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017017143.3XP_016872632.1  small acidic protein isoform X1

      Conserved Domains (1) summary
      pfam15477
      Location:159
      SMAP; Small acidic protein family
    2. XM_047426310.1XP_047282266.1  small acidic protein isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      16836026..16855719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001142705.1: Suppressed sequence

      Description
      NM_001142705.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.