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    Tspan9 tetraspanin 9 [ Mus musculus (house mouse) ]

    Gene ID: 109246, updated on 18-Sep-2024

    Summary

    Official Symbol
    Tspan9provided by MGI
    Official Full Name
    tetraspanin 9provided by MGI
    Primary source
    MGI:MGI:1924558
    See related
    Ensembl:ENSMUSG00000030352 AllianceGenome:MGI:1924558
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tspan-9; 6720474K14Rik; 9430079M16Rik
    Summary
    Located in membrane. Is expressed in several structures, including central nervous system; diaphragm; gut; limb segment; and skeletal musculature. Orthologous to human TSPAN9 (tetraspanin 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung adult (RPKM 33.3), cerebellum adult (RPKM 22.3) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tspan9 in Genome Data Viewer
    Location:
    6 F3; 6 62.73 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (127938359..128120541, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (127961396..128143578, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38901 Neighboring gene predicted gene, 40401 Neighboring gene tetraspanin 11 Neighboring gene STARR-seq mESC enhancer starr_17424 Neighboring gene predicted gene, 38903 Neighboring gene predicted gene 15870 Neighboring gene predicted gene, 53341 Neighboring gene predicted gene, 34416 Neighboring gene predicted gene, 52879 Neighboring gene STARR-seq mESC enhancer starr_17429 Neighboring gene RIKEN cDNA 9330102E08 gene Neighboring gene Rho GTPase activating protein 20 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5)  1 citation
    • Gene trapped (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in migrasome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in tetraspanin-enriched microdomain ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tetraspanin-9
    Names
    tetraspan NET-5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356301.2NP_001343230.1  tetraspanin-9 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 1 and 3-5, encodes isoform b.
      Source sequence(s)
      AC135355, AC144778
      Consensus CDS
      CCDS20568.1
      UniProtKB/Swiss-Prot
      Q3TQQ0, Q8BJU2
      Related
      ENSMUSP00000107796.2, ENSMUST00000112173.8
      Conserved Domains (2) summary
      cd03165
      Location:105202
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:9226
      Tetraspannin; Tetraspanin family
    2. NM_001379133.1NP_001366062.1  tetraspanin-9 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 1, 2, 4, and 5, encodes isoform b.
      Source sequence(s)
      AC135355, AC144778
      UniProtKB/Swiss-Prot
      Q3TQQ0, Q8BJU2
      Conserved Domains (2) summary
      cd03165
      Location:105202
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:9226
      Tetraspannin; Tetraspanin family
    3. NM_001379134.1NP_001366063.1  tetraspanin-9 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variants 1-3 and 5, encodes isoform b.
      Source sequence(s)
      AC135355, AC144778
      UniProtKB/Swiss-Prot
      Q3TQQ0, Q8BJU2
      Conserved Domains (2) summary
      cd03165
      Location:105202
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:9226
      Tetraspannin; Tetraspanin family
    4. NM_001379135.1NP_001366064.1  tetraspanin-9 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 1-4, encodes isoform b.
      Source sequence(s)
      AC135355, AC144778
      UniProtKB/Swiss-Prot
      Q3TQQ0, Q8BJU2
      Conserved Domains (2) summary
      cd03165
      Location:105202
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:9226
      Tetraspannin; Tetraspanin family
    5. NM_001379136.1NP_001366065.1  tetraspanin-9 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) represents the longest transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC135355
      Conserved Domains (2) summary
      cd03165
      Location:196293
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:100317
      Tetraspannin; Tetraspanin family
    6. NM_175414.6NP_780623.1  tetraspanin-9 isoform b

      See identical proteins and their annotated locations for NP_780623.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), as well as variants 2-5, encodes isoform b.
      Source sequence(s)
      AC135355, AC144778
      Consensus CDS
      CCDS20568.1
      UniProtKB/Swiss-Prot
      Q3TQQ0, Q8BJU2
      Related
      ENSMUSP00000032503.6, ENSMUST00000032503.12
      Conserved Domains (2) summary
      cd03165
      Location:105202
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:9226
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      127938359..128120541 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255085.1XP_030110945.1  tetraspanin-9 isoform X1

      Conserved Domains (2) summary
      cd03165
      Location:142239
      NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:46263
      Tetraspannin; Tetraspanin family