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    Gins4 GINS complex subunit 4 (Sld5 homolog) [ Mus musculus (house mouse) ]

    Gene ID: 109145, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gins4provided by MGI
    Official Full Name
    GINS complex subunit 4 (Sld5 homolog)provided by MGI
    Primary source
    MGI:MGI:1923847
    See related
    Ensembl:ENSMUSG00000031546
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sld5; 2810037C03Rik; 4933405K01Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 22.2), liver E14 (RPKM 21.2) and 26 other tissues See more
    Orthologs

    Genomic context

    See Gins4 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (23226610..23237668, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (24337082..24348140, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30306 Neighboring gene predicted gene, 30247 Neighboring gene glycerol-3-phosphate acyltransferase 4 Neighboring gene golgi autoantigen, golgin subfamily a, 7 Neighboring gene predicted gene, 39141 Neighboring gene predicted gene, 30370

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to 3'-5' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-dependent DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    double-strand break repair via break-induced replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    inner cell mass cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    GINS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    replication fork protection complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    DNA replication complex GINS protein SLD5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024240.6NP_077202.1  DNA replication complex GINS protein SLD5

      See identical proteins and their annotated locations for NP_077202.1

      Status: VALIDATED

      Source sequence(s)
      AK076104, BB750165, BG342391, BY309805
      Consensus CDS
      CCDS22190.1
      UniProtKB/Swiss-Prot
      Q99LZ3
      Related
      ENSMUSP00000033950.5, ENSMUST00000033950.6
      Conserved Domains (3) summary
      cd11711
      Location:26146
      GINS_A_Sld5; Alpha-helical domain of GINS complex protein Sld5
      COG5086
      Location:23223
      COG5086; Uncharacterized conserved protein [Function unknown]
      pfam16922
      Location:165223
      SLD5_C; DNA replication complex GINS protein SLD5 C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      23226610..23237668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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