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    Plekha5 pleckstrin homology domain containing, family A member 5 [ Mus musculus (house mouse) ]

    Gene ID: 109135, updated on 2-Oct-2018

    Summary

    Official Symbol
    Plekha5provided by MGI
    Official Full Name
    pleckstrin homology domain containing, family A member 5provided by MGI
    Primary source
    MGI:MGI:1923802
    See related
    Ensembl:ENSMUSG00000030231 Vega:OTTMUSG00000056993
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pepp2; AMH-Cre; Ayu21-9; AI428202; AK129423; 2810431N21Rik; Gt(pU21)9Imeg; Tg(AMH-cre)1Flor
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 10.9), CNS E14 (RPKM 9.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Plekha5 in Genome Data Viewer
    Location:
    6; 6 G2
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (140423639..140597110)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (140372620..140543427)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 38917 Neighboring gene predicted gene 5051 Neighboring gene AE binding protein 2 Neighboring gene predicted gene, 38918 Neighboring gene predicted gene, 30215 Neighboring gene ribosomal protein L38, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38455

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    reproductive system development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density EXP
    Inferred from Experiment
    more info
    PubMed 
    postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    pleckstrin homology domain-containing family A member 5
    Names
    Gt(Ayu21)9Imeg
    phosphoinositol 3-phosphate-binding protein-2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144920.3NP_659169.3  pleckstrin homology domain-containing family A member 5

      Status: VALIDATED

      Source sequence(s)
      AK129423, CJ170110
      Consensus CDS
      CCDS39688.1
      UniProtKB/TrEMBL
      E9Q6H8, Q6ZPK1
      Related
      ENSMUSP00000084904.3, OTTMUSP00000073580, ENSMUST00000087622.5, OTTMUST00000140449
      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      140423639..140597110
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506863.2XP_006506926.1  pleckstrin homology domain-containing family A member 5 isoform X1

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    2. XM_006506864.2XP_006506927.1  pleckstrin homology domain-containing family A member 5 isoform X6

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    3. XM_006506869.2XP_006506932.1  pleckstrin homology domain-containing family A member 5 isoform X12

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    4. XM_017321307.1XP_017176796.1  pleckstrin homology domain-containing family A member 5 isoform X2

      UniProtKB/TrEMBL
      E9Q6H8
      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    5. XM_017321309.1XP_017176798.1  pleckstrin homology domain-containing family A member 5 isoform X13

    6. XM_006506866.2XP_006506929.1  pleckstrin homology domain-containing family A member 5 isoform X9

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    7. XM_006506861.2XP_006506924.1  pleckstrin homology domain-containing family A member 5 isoform X4

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    8. XM_006506862.2XP_006506925.1  pleckstrin homology domain-containing family A member 5 isoform X5

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    9. XM_006506865.2XP_006506928.1  pleckstrin homology domain-containing family A member 5 isoform X8

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    10. XM_006506867.2XP_006506930.1  pleckstrin homology domain-containing family A member 5 isoform X10

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    11. XM_006506868.2XP_006506931.1  pleckstrin homology domain-containing family A member 5 isoform X11

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    12. XM_006506870.2XP_006506933.1  pleckstrin homology domain-containing family A member 5 isoform X14

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    13. XM_006506871.2XP_006506934.1  pleckstrin homology domain-containing family A member 5 isoform X15

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    14. XM_006506879.2XP_006506942.1  pleckstrin homology domain-containing family A member 5 isoform X23

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    15. XM_006506872.2XP_006506935.1  pleckstrin homology domain-containing family A member 5 isoform X16

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    16. XM_006506873.2XP_006506936.1  pleckstrin homology domain-containing family A member 5 isoform X17

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    17. XM_006506880.2XP_006506943.1  pleckstrin homology domain-containing family A member 5 isoform X24

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    18. XM_006506874.2XP_006506937.1  pleckstrin homology domain-containing family A member 5 isoform X18

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    19. XM_006506878.2XP_006506941.1  pleckstrin homology domain-containing family A member 5 isoform X22

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    20. XM_006506883.2XP_006506946.1  pleckstrin homology domain-containing family A member 5 isoform X27

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    21. XM_006506860.2XP_006506923.1  pleckstrin homology domain-containing family A member 5 isoform X3

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    22. XM_006506898.2XP_006506961.1  pleckstrin homology domain-containing family A member 5 isoform X41

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    23. XM_006506875.2XP_006506938.1  pleckstrin homology domain-containing family A member 5 isoform X19

      Related
      ENSMUSP00000145478.1, OTTMUSP00000073582, ENSMUST00000203517.2, OTTMUST00000140451
      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    24. XM_006506881.2XP_006506944.1  pleckstrin homology domain-containing family A member 5 isoform X25

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    25. XM_006506882.2XP_006506945.1  pleckstrin homology domain-containing family A member 5 isoform X26

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    26. XM_017321308.1XP_017176797.1  pleckstrin homology domain-containing family A member 5 isoform X7

    27. XM_006506892.2XP_006506955.1  pleckstrin homology domain-containing family A member 5 isoform X35

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    28. XM_011241564.2XP_011239866.1  pleckstrin homology domain-containing family A member 5 isoform X33

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    29. XM_006506893.2XP_006506956.1  pleckstrin homology domain-containing family A member 5 isoform X36

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    30. XM_006506894.2XP_006506957.1  pleckstrin homology domain-containing family A member 5 isoform X37

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    31. XM_006506895.2XP_006506958.1  pleckstrin homology domain-containing family A member 5 isoform X38

      Conserved Domains (3) summary
      cd13248
      Location:165268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:171267
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
    32. XM_006506896.2XP_006506959.1  pleckstrin homology domain-containing family A member 5 isoform X39

      Related
      ENSMUSP00000145457.1, OTTMUSP00000073581, ENSMUST00000204145.2, OTTMUST00000140450
      Conserved Domains (3) summary
      pfam00169
      Location:171238
      PH; PH domain
      pfam00397
      Location:5988
      WW; WW domain
      cl17171
      Location:165238
      PH-like; Pleckstrin homology-like domain
    33. XM_006506897.2XP_006506960.1  pleckstrin homology domain-containing family A member 5 isoform X40

      Conserved Domains (1) summary
      pfam00397
      Location:1342
      WW; WW domain
    34. XM_006506876.3XP_006506939.1  pleckstrin homology domain-containing family A member 5 isoform X20

      See identical proteins and their annotated locations for XP_006506939.1

      Conserved Domains (2) summary
      cd13248
      Location:56159
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:62158
      PH; PH domain
    35. XM_017321310.1XP_017176799.1  pleckstrin homology domain-containing family A member 5 isoform X21

    36. XM_006506877.3XP_006506940.1  pleckstrin homology domain-containing family A member 5 isoform X20

      See identical proteins and their annotated locations for XP_006506940.1

      Conserved Domains (2) summary
      cd13248
      Location:56159
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:62158
      PH; PH domain
    37. XM_006506887.2XP_006506950.1  pleckstrin homology domain-containing family A member 5 isoform X31

      See identical proteins and their annotated locations for XP_006506950.1

      Conserved Domains (1) summary
      COG1196
      Location:360625
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    38. XM_006506889.2XP_006506952.1  pleckstrin homology domain-containing family A member 5 isoform X32

      See identical proteins and their annotated locations for XP_006506952.1

      Conserved Domains (1) summary
      COG1196
      Location:354619
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    39. XM_006506884.2XP_006506947.1  pleckstrin homology domain-containing family A member 5 isoform X28

      Conserved Domains (1) summary
      cl17171
      Location:2352
      PH-like; Pleckstrin homology-like domain
    40. XM_006506885.2XP_006506948.1  pleckstrin homology domain-containing family A member 5 isoform X29

      Conserved Domains (1) summary
      cl17171
      Location:1544
      PH-like; Pleckstrin homology-like domain
    41. XM_006506886.2XP_006506949.1  pleckstrin homology domain-containing family A member 5 isoform X30

      Conserved Domains (1) summary
      cl17171
      Location:1544
      PH-like; Pleckstrin homology-like domain
    42. XM_006506891.2XP_006506954.1  pleckstrin homology domain-containing family A member 5 isoform X34

      Conserved Domains (1) summary
      cl17171
      Location:1544
      PH-like; Pleckstrin homology-like domain
    43. XM_006506888.2XP_006506951.1  pleckstrin homology domain-containing family A member 5 isoform X31

      See identical proteins and their annotated locations for XP_006506951.1

      Conserved Domains (1) summary
      COG1196
      Location:360625
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    44. XM_006506890.2XP_006506953.1  pleckstrin homology domain-containing family A member 5 isoform X32

      See identical proteins and their annotated locations for XP_006506953.1

      Conserved Domains (1) summary
      COG1196
      Location:354619
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_001785082.1 RNA Sequence

    2. XR_378093.2 RNA Sequence

    3. XR_001785083.1 RNA Sequence

    4. XR_378094.2 RNA Sequence

    5. XR_378095.2 RNA Sequence

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