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    Zzz3 zinc finger, ZZ domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 108946, updated on 22-Aug-2021

    Summary

    Official Symbol
    Zzz3provided by MGI
    Official Full Name
    zinc finger, ZZ domain containing 3provided by MGI
    Primary source
    MGI:MGI:1920453
    See related
    Ensembl:ENSMUSG00000039068
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R75514; AA408566; AI481057; AW556059; 3110065C23Rik; 6430567E01Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 9.9), CNS E18 (RPKM 7.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zzz3 in Genome Data Viewer
    Location:
    3; 3 H3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (152101110..152168463)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (152395473..152462826)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (152058974..152125790)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm72 Neighboring gene mitoguardin 1 Neighboring gene ubiquitin specific peptidase 33 Neighboring gene uncharacterized LOC118568621 Neighboring gene RIKEN cDNA 3110067G11 gene Neighboring gene adenylate kinase 5 Neighboring gene expressed sequence AI115009

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in histone H4 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of ATAC complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ZZ-type zinc finger-containing protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080755.2NP_001074224.1  ZZ-type zinc finger-containing protein 3 isoform a

      See identical proteins and their annotated locations for NP_001074224.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC111139, AC122529
      Consensus CDS
      CCDS38674.1
      UniProtKB/Swiss-Prot
      Q6KAQ7
      Related
      ENSMUSP00000101706.3, ENSMUST00000106100.9
      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    2. NM_001287139.1NP_001274068.1  ZZ-type zinc finger-containing protein 3 isoform b

      See identical proteins and their annotated locations for NP_001274068.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded protein (isoform b) is shorter than isoform a.
      Source sequence(s)
      AC111139, BC060614, BY305239
      Consensus CDS
      CCDS71338.1
      UniProtKB/TrEMBL
      D3YTT9
      Related
      ENSMUSP00000087428.5, ENSMUST00000089982.11
      Conserved Domains (3) summary
      cd02341
      Location:827877
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:661709
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    3. NM_001346655.1NP_001333584.1  ZZ-type zinc finger-containing protein 3 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC111139, AK165882
      Consensus CDS
      CCDS84698.1
      UniProtKB/Swiss-Prot
      Q6KAQ7
      Related
      ENSMUSP00000101709.2, ENSMUST00000106103.8
      Conserved Domains (2) summary
      cd02341
      Location:327377
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:161209
      Myb_DNA-binding; Myb-like DNA-binding domain
    4. NM_001355673.1NP_001342602.1  ZZ-type zinc finger-containing protein 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC111139, AC122529
      Consensus CDS
      CCDS38674.1
      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      152101110..152168463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319423.3XP_017174912.1  ZZ-type zinc finger-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6KAQ7
      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    2. XM_006500852.5XP_006500915.1  ZZ-type zinc finger-containing protein 3 isoform X2

      See identical proteins and their annotated locations for XP_006500915.1

      UniProtKB/TrEMBL
      D3YTT9
      Conserved Domains (3) summary
      cd02341
      Location:827877
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:661709
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    3. XM_011239984.4XP_011238286.1  ZZ-type zinc finger-containing protein 3 isoform X3

      Conserved Domains (1) summary
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    4. XM_006500854.5XP_006500917.1  ZZ-type zinc finger-containing protein 3 isoform X5

      Conserved Domains (1) summary
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    5. XM_006500853.5XP_006500916.1  ZZ-type zinc finger-containing protein 3 isoform X4

      Conserved Domains (1) summary
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    6. XM_006500857.5XP_006500920.1  ZZ-type zinc finger-containing protein 3 isoform X8

      See identical proteins and their annotated locations for XP_006500920.1

      UniProtKB/Swiss-Prot
      Q6KAQ7
      Conserved Domains (2) summary
      cd02341
      Location:327377
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:161209
      Myb_DNA-binding; Myb-like DNA-binding domain
    7. XM_006500855.5XP_006500918.1  ZZ-type zinc finger-containing protein 3 isoform X6

      Conserved Domains (2) summary
      cd02341
      Location:332382
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:166214
      Myb_DNA-binding; Myb-like DNA-binding domain
    8. XM_036162811.1XP_036018704.1  ZZ-type zinc finger-containing protein 3 isoform X4

      Conserved Domains (1) summary
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    9. XM_006500856.5XP_006500919.1  ZZ-type zinc finger-containing protein 3 isoform X7

      See identical proteins and their annotated locations for XP_006500919.1

      UniProtKB/Swiss-Prot
      Q6KAQ7
      Related
      ENSMUSP00000143693.2, ENSMUST00000200570.5
      Conserved Domains (2) summary
      cd02341
      Location:331381
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:165213
      Myb_DNA-binding; Myb-like DNA-binding domain
    10. XM_030252353.2XP_030108213.1  ZZ-type zinc finger-containing protein 3 isoform X8

      Conserved Domains (2) summary
      cd02341
      Location:327377
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:161209
      Myb_DNA-binding; Myb-like DNA-binding domain
    11. XM_006500848.5XP_006500911.1  ZZ-type zinc finger-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006500911.1

      UniProtKB/Swiss-Prot
      Q6KAQ7
      Related
      ENSMUSP00000101707.2, ENSMUST00000106101.2
      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    12. XM_030252350.2XP_030108210.1  ZZ-type zinc finger-containing protein 3 isoform X1

      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein
    13. XM_030252352.2XP_030108212.1  ZZ-type zinc finger-containing protein 3 isoform X6

      Conserved Domains (2) summary
      cd02341
      Location:332382
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:166214
      Myb_DNA-binding; Myb-like DNA-binding domain
    14. XM_006500850.4XP_006500913.1  ZZ-type zinc finger-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006500913.1

      UniProtKB/Swiss-Prot
      Q6KAQ7
      Conserved Domains (3) summary
      cd02341
      Location:828878
      ZZ_ZZZ3; Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      pfam00249
      Location:662710
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam14757
      Location:343418
      NSP2-B_epitope; Immunogenic region of nsp2 protein of arterivirus polyprotein

    RNA

    1. XR_867209.4 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198416.2: Suppressed sequence

      Description
      NM_198416.2: This RefSeq was permanently suppressed because currently there is support for the protein but not for the transcript.
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