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    Cdca2 cell division cycle associated 2 [ Mus musculus (house mouse) ]

    Gene ID: 108912, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cdca2provided by MGI
    Official Full Name
    cell division cycle associated 2provided by MGI
    Primary source
    MGI:MGI:1919787
    See related
    Ensembl:ENSMUSG00000048922
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI586158; 2610311M19Rik
    Expression
    Biased expression in testis adult (RPKM 12.3), CNS E11.5 (RPKM 7.2) and 12 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cdca2 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (67910629..67953290, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (67673180..67715841, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (68294411..68333898, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38409 Neighboring gene predicted gene, 24981 Neighboring gene potassium channel tetramerisation domain containing 9 Neighboring gene gonadotropin releasing hormone 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome segregation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cell division cycle-associated protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110162.1NP_001103632.1  cell division cycle-associated protein 2

      See identical proteins and their annotated locations for NP_001103632.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript.
      Source sequence(s)
      AK160223, AK166952, BC067009, CD354922
      Consensus CDS
      CCDS36962.2
      UniProtKB/Swiss-Prot
      Q14B71
      Related
      ENSMUSP00000127571.2, ENSMUST00000163100.8
      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding
    2. NM_175384.4NP_780593.3  cell division cycle-associated protein 2

      See identical proteins and their annotated locations for NP_780593.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC067009, BC075682
      Consensus CDS
      CCDS36962.2
      UniProtKB/Swiss-Prot
      Q14B71
      Related
      ENSMUSP00000117847.3, ENSMUST00000150006.9
      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      67910629..67953290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247603.1XP_030103463.1  cell division cycle-associated protein 2 isoform X3

      Conserved Domains (1) summary
      pfam15276
      Location:379434
      PP1_bind; Protein phosphatase 1 binding
    2. XM_030247602.2XP_030103462.1  cell division cycle-associated protein 2 isoform X2

      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding
    3. XM_006518420.5XP_006518483.1  cell division cycle-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006518483.1

      UniProtKB/Swiss-Prot
      Q14B71
      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding
    4. XM_030247604.2XP_030103464.1  cell division cycle-associated protein 2 isoform X4

      Conserved Domains (1) summary
      pfam15276
      Location:379434
      PP1_bind; Protein phosphatase 1 binding
    5. XM_011244913.4XP_011243215.1  cell division cycle-associated protein 2 isoform X3

      Conserved Domains (1) summary
      pfam15276
      Location:379434
      PP1_bind; Protein phosphatase 1 binding
    6. XM_011244912.4XP_011243214.1  cell division cycle-associated protein 2 isoform X2

      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding
    7. XM_030247605.1XP_030103465.1  cell division cycle-associated protein 2 isoform X6

      Conserved Domains (1) summary
      pfam15276
      Location:234289
      PP1_bind; Protein phosphatase 1 binding
    8. XM_006518423.2XP_006518486.1  cell division cycle-associated protein 2 isoform X5

      Conserved Domains (1) summary
      pfam15276
      Location:234289
      PP1_bind; Protein phosphatase 1 binding
    9. XM_011244915.4XP_011243217.1  cell division cycle-associated protein 2 isoform X7

      Related
      ENSMUSP00000115633.2, ENSMUST00000132705.8
      Conserved Domains (1) summary
      pfam15276
      Location:380435
      PP1_bind; Protein phosphatase 1 binding
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