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    Rnf187 ring finger protein 187 [ Mus musculus (house mouse) ]

    Gene ID: 108660, updated on 27-Jan-2018

    Summary

    Official Symbol
    Rnf187provided by MGI
    Official Full Name
    ring finger protein 187provided by MGI
    Primary source
    MGI:MGI:1914224
    See related
    Ensembl:ENSMUSG00000020496 Vega:OTTMUSG00000005779
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RACO-1; AB030190; 2410016F01Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 227.2), whole brain E14.5 (RPKM 200.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rnf187 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (58932288..58938906, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (58745790..58752408, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12257 Neighboring gene butyrophilin-like 10 Neighboring gene histone cluster 3, H2ba Neighboring gene histone cluster 3, H2bb, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein autoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF187
    Names
    RING domain AP1 coactivator 1
    RING-type E3 ubiquitin transferase RNF187
    protein RNF187
    NP_071868.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022423.2NP_071868.2  E3 ubiquitin-protein ligase RNF187

      See identical proteins and their annotated locations for NP_071868.2

      Status: VALIDATED

      Source sequence(s)
      BC072613, CJ180431
      Consensus CDS
      CCDS78953.1
      UniProtKB/Swiss-Prot
      Q8BFX1
      Related
      ENSMUSP00000091703.6, OTTMUSP00000005943, ENSMUST00000094151.5, OTTMUST00000012796
      Conserved Domains (1) summary
      pfam00097
      Location:1252
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      58932288..58938906 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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