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    Med21 mediator complex subunit 21 [ Mus musculus (house mouse) ]

    Gene ID: 108098, updated on 23-Jun-2021

    Summary

    Official Symbol
    Med21provided by MGI
    Official Full Name
    mediator complex subunit 21provided by MGI
    Primary source
    MGI:MGI:1347064
    See related
    Ensembl:ENSMUSG00000030291
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sr; Sur; Srb7; Surb7; D19234; AI449604; D6Ertd782; D6Ertd782e; 0610007L03Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 38.3), limb E14.5 (RPKM 28.4) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Med21 in Genome Data Viewer
    Location:
    6 G3; 6 77.7 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (146544077..146552098)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (146642579..146650600)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (146591101..146599122)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene FGFR1 oncogene partner 2 Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene RIKEN cDNA 4930479D17 gene Neighboring gene predicted pseudogene 6654 Neighboring gene serine/threonine kinase 38 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mediator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 21
    Names
    RNA polymerase II holoenzyme component SRB7
    RNAPII complex component SRB7
    SRB7 (supressor of RNA polymerase B) homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025315.3NP_079591.1  mediator of RNA polymerase II transcription subunit 21

      See identical proteins and their annotated locations for NP_079591.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124128
      Consensus CDS
      CCDS20700.1
      UniProtKB/Swiss-Prot
      Q9CQ39
      Related
      ENSMUSP00000032429.3, ENSMUST00000032429.9
      Conserved Domains (1) summary
      pfam11221
      Location:1127
      Med21; Subunit 21 of Mediator complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      146544077..146552098
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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