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    Cdc20 cell division cycle 20 [ Mus musculus (house mouse) ]

    Gene ID: 107995, updated on 5-Feb-2019

    Summary

    Official Symbol
    Cdc20provided by MGI
    Official Full Name
    cell division cycle 20provided by MGI
    Primary source
    MGI:MGI:1859866
    See related
    Ensembl:ENSMUSG00000006398
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C87100; p55CDC; 2310042N09Rik
    Expression
    Broad expression in liver E14.5 (RPKM 69.5), liver E14 (RPKM 66.0) and 17 other tissues See more
    Orthologs

    Genomic context

    See Cdc20 in Genome Data Viewer
    Location:
    4; 4 D2.1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (118432901..118437343, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (118105506..118109948, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene hydroxypyruvate isomerase (putative) Neighboring gene seizure threshold 2 Neighboring gene mediator complex subunit 8 Neighboring gene elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 Neighboring gene myeloproliferative leukemia virus oncogene Neighboring gene tyrosine kinase with immunoglobulin-like and EGF-like domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    anaphase-promoting complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone deacetylase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin-protein transferase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    anaphase-promoting complex-dependent catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic sister chromatid cohesion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mitotic spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synapse maturation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of synaptic plasticity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of dendrite development ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of meiotic nuclear division IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cell division cycle protein 20 homolog
    Names
    cell division cycle 20 homolog
    mmCdc20

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023223.2NP_075712.2  cell division cycle protein 20 homolog

      See identical proteins and their annotated locations for NP_075712.2

      Status: VALIDATED

      Source sequence(s)
      AK168650, AV499208, BY736811
      Consensus CDS
      CCDS18551.1
      UniProtKB/Swiss-Prot
      Q9JJ66
      Related
      ENSMUSP00000006565.6, ENSMUST00000006565.12
      Conserved Domains (3) summary
      COG2319
      Location:183473
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:190471
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:229266
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      118432901..118437343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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