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    Arl2bp ADP-ribosylation factor-like 2 binding protein [ Mus musculus (house mouse) ]

    Gene ID: 107566, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arl2bpprovided by MGI
    Official Full Name
    ADP-ribosylation factor-like 2 binding proteinprovided by MGI
    Primary source
    MGI:MGI:1349429
    See related
    Ensembl:ENSMUSG00000031776
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BART; Bart1; AI482273; AI849834; 1700010P10Rik; 1700027H16Rik; 6330544B05Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 119.3), CNS E11.5 (RPKM 53.4) and 27 other tissues See more
    Orthologs

    Genomic context

    See Arl2bp in Genome Data Viewer
    Location:
    8; 8 C5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (94666600..94674457)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (97190655..97198322)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 192, member A Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene plasma membrane proteolipid Neighboring gene nuclear encoded tRNA leucine 5 (anticodon CAG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    GTPase regulator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    maintenance of protein location in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of tyrosine phosphorylation of STAT protein ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cilium IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 2-binding protein
    Names
    ADP-ribosylation-like 2 binding protein
    ARF-like 2-binding protein
    binder of ARF2 protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024191.2NP_077153.1  ADP-ribosylation factor-like protein 2-binding protein isoform 1

      See identical proteins and their annotated locations for NP_077153.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
      Source sequence(s)
      AC123826, AK018229, BY159929
      Consensus CDS
      CCDS22545.1
      UniProtKB/Swiss-Prot
      Q9D385
      Related
      ENSMUSP00000034228.8, ENSMUST00000034228.15
      Conserved Domains (1) summary
      pfam11527
      Location:25132
      ARL2_Bind_BART; The ARF-like 2 binding protein BART
    2. NM_024269.4NP_077231.1  ADP-ribosylation factor-like protein 2-binding protein isoform 2

      See identical proteins and their annotated locations for NP_077231.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC123826, AK006418
      Consensus CDS
      CCDS40440.1
      UniProtKB/Swiss-Prot
      Q9D385
      Related
      ENSMUSP00000105153.4, ENSMUST00000109527.5
      Conserved Domains (1) summary
      pfam11527
      Location:14121
      ARL2_Bind_BART; The ARF-like 2 binding protein BART

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      94666600..94674457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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