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    Btaf1 B-TFIID TATA-box binding protein associated factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 107182, updated on 22-Aug-2021

    Summary

    Official Symbol
    Btaf1provided by MGI
    Official Full Name
    B-TFIID TATA-box binding protein associated factor 1provided by MGI
    Primary source
    MGI:MGI:2147538
    See related
    Ensembl:ENSMUSG00000040565
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TAF170; AI414500; AI447930; E430027O22Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 6.3), liver E14 (RPKM 5.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Btaf1 in Genome Data Viewer
    Location:
    19; 19 C2
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (36903479..36991457)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (36926079..37014057)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (37000569..37088547)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1641 Neighboring gene fibroblast growth factor binding protein 3 Neighboring gene cytoplasmic polyadenylation element binding protein 3 Neighboring gene RIKEN cDNA A330032B11 gene Neighboring gene membrane associated ring-CH-type finger 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Chemically induced (ENU) (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP-dependent activity, acting on DNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ATP-dependent activity, acting on DNA ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription coregulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    TATA-binding protein-associated factor 172
    Names
    BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)
    TBP-associated factor 170

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080706.1NP_001074175.1  TATA-binding protein-associated factor 172

      Status: PROVISIONAL

      Source sequence(s)
      AC118931
      Consensus CDS
      CCDS37969.1
      UniProtKB/TrEMBL
      E9QAE3
      Related
      ENSMUSP00000097093.4, ENSMUST00000099494.4
      Conserved Domains (6) summary
      cd00046
      Location:12851434
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:12681584
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:16431743
      Helicase_C; Helicase conserved C-terminal domain
      pfam12054
      Location:5851050
      DUF3535; Domain of unknown function (DUF3535)
      pfam13513
      Location:402453
      HEAT_EZ; HEAT-like repeat
      sd00044
      Location:351376
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      36903479..36991457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161373.1XP_036017266.1  TATA-binding protein-associated factor 172 isoform X1

      Conserved Domains (4) summary
      COG0553
      Location:10731645
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      sd00044
      Location:196221
      HEAT; HEAT repeat [structural motif]
      cd17999
      Location:11101347
      DEXHc_Mot1; DEXH-box helicase domain of Mot1
      pfam12054
      Location:430895
      DUF3535; Domain of unknown function (DUF3535)
    2. XM_006526561.5XP_006526624.1  TATA-binding protein-associated factor 172 isoform X2

      Conserved Domains (4) summary
      COG0553
      Location:10261598
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      sd00044
      Location:149174
      HEAT; HEAT repeat [structural motif]
      cd17999
      Location:10631300
      DEXHc_Mot1; DEXH-box helicase domain of Mot1
      pfam12054
      Location:383848
      DUF3535; Domain of unknown function (DUF3535)
    3. XM_030250684.2XP_030106544.1  TATA-binding protein-associated factor 172 isoform X3

      Conserved Domains (4) summary
      COG0553
      Location:4561028
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      sd00044
      Location:335363
      HEAT; HEAT repeat [structural motif]
      cd17999
      Location:493730
      DEXHc_Mot1; DEXH-box helicase domain of Mot1
      pfam12054
      Location:1278
      DUF3535; Domain of unknown function (DUF3535)
    4. XM_017318039.3XP_017173528.1  TATA-binding protein-associated factor 172 isoform X3

      Conserved Domains (4) summary
      COG0553
      Location:4561028
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      sd00044
      Location:335363
      HEAT; HEAT repeat [structural motif]
      cd17999
      Location:493730
      DEXHc_Mot1; DEXH-box helicase domain of Mot1
      pfam12054
      Location:1278
      DUF3535; Domain of unknown function (DUF3535)
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