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    Rrp12 ribosomal RNA processing 12 homolog [ Mus musculus (house mouse) ]

    Gene ID: 107094, updated on 26-Sep-2022

    Summary

    Official Symbol
    Rrp12provided by MGI
    Official Full Name
    ribosomal RNA processing 12 homologprovided by MGI
    Primary source
    MGI:MGI:2147437
    See related
    Ensembl:ENSMUSG00000035049 AllianceGenome:MGI:2147437
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0690
    Summary
    Predicted to be involved in rRNA processing. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. Predicted to be active in nucleolus. Orthologous to human RRP12 (ribosomal RNA processing 12 homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 14.1), CNS E11.5 (RPKM 6.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rrp12 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (41847922..41884592, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (41859483..41896153, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene frequently rearranged in advanced T cell lymphomas Neighboring gene frequently rearranged in advanced T cell lymphomas 2 Neighboring gene predicted gene, 46644 Neighboring gene phosphoglycerate mutase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199447.2NP_955518.1  RRP12-like protein

      See identical proteins and their annotated locations for NP_955518.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062977
      Consensus CDS
      CCDS29814.1
      UniProtKB/Swiss-Prot
      Q6P5B0, Q80TU2
      UniProtKB/TrEMBL
      Q3UJA1
      Related
      ENSMUSP00000039853.4, ENSMUST00000038677.5
      Conserved Domains (2) summary
      pfam08161
      Location:473670
      NUC173; NUC173 domain
      pfam14632
      Location:11571204
      SPT6_acidic; Acidic N-terminal SPT6

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      41847922..41884592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250683.1XP_030106543.1  RRP12-like protein isoform X1

      Conserved Domains (1) summary
      pfam08161
      Location:2192
      NUC173; NUC173 domain