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    Scaf8 SR-related CTD-associated factor 8 [ Mus musculus (house mouse) ]

    Gene ID: 106583, updated on 12-Aug-2018

    Summary

    Official Symbol
    Scaf8provided by MGI
    Official Full Name
    SR-related CTD-associated factor 8provided by MGI
    Primary source
    MGI:MGI:1925212
    See related
    Ensembl:ENSMUSG00000046201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rbm16; AA408306; AI447644; AI448652; AU015035; mKIAA1116; A630086M08Rik; A930036P18Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 17.4), limb E14.5 (RPKM 13.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Scaf8 in Genome Data Viewer
    Location:
    17; 17 A1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (3114972..3198859)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (3114972..3198859)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108168313 Neighboring gene NLR family, pyrin domain containing 2 pseudogene Neighboring gene solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 pseudogene Neighboring gene 60S ribosomal protein L34 pseudogene Neighboring gene myosin, light chain 12B, regulatory pseudogene Neighboring gene predicted gene, 34035 Neighboring gene CD2-associated protein pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1116

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase core enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    termination of RNA polymerase II transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA cleavage factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein SCAF8
    Names
    CTD-binding SR-like protein rA8
    RNA binding motif protein 16
    SR-like CTD-associated factor 8
    SR-related and CTD-associated factor 8
    putative RNA-binding protein 16

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134123.3NP_598884.2  protein SCAF8

      See identical proteins and their annotated locations for NP_598884.2

      Status: VALIDATED

      Source sequence(s)
      AK042381, BC075621, CA560428
      Consensus CDS
      CCDS49927.1
      UniProtKB/Swiss-Prot
      Q6DID3
      UniProtKB/TrEMBL
      Q8C9D3
      Related
      ENSMUSP00000076024.6, ENSMUST00000076734.7
      Conserved Domains (3) summary
      COG0724
      Location:473552
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd03562
      Location:4125
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...
      cd12462
      Location:475553
      RRM_SCAF8; RNA recognition motif in SR-related and CTD-associated factor 8 (SCAF8) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      3114972..3198859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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