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    Tecr trans-2,3-enoyl-CoA reductase [ Mus musculus (house mouse) ]

    Gene ID: 106529, updated on 16-Oct-2021

    Summary

    Official Symbol
    Tecrprovided by MGI
    Official Full Name
    trans-2,3-enoyl-CoA reductaseprovided by MGI
    Primary source
    MGI:MGI:1915408
    See related
    Ensembl:ENSMUSG00000031708
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SC2; Gpsn2; AI173355; D17Ertd178e; 2410016D23Rik; A230102P12Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 340.9), mammary gland adult (RPKM 233.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Tecr in Genome Data Viewer
    Location:
    8 C2; 8 40.22 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (84298327..84321120, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (83571698..83594491, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (86095597..86118390, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S2 pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit B7 Neighboring gene RIKEN cDNA D830024N08 gene Neighboring gene predicted gene, 51541 Neighboring gene predicted gene, 42029 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene DnaJ heat shock protein family (Hsp40) member B1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC144249

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables oxidoreductase activity, acting on the CH-CH group of donors IEA
    Inferred from Electronic Annotation
    more info
     
    enables very-long-chain enoyl-CoA reductase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid elongation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sphingolipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in very long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in very long-chain fatty acid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    very-long-chain enoyl-CoA reductase
    Names
    TER
    glycoprotein, synaptic 2
    synaptic glycoprotein SC2
    NP_081455.1
    NP_598879.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027179.1NP_081455.1  very-long-chain enoyl-CoA reductase isoform 2

      See identical proteins and their annotated locations for NP_081455.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK010984, BE994003, BY278351
      Consensus CDS
      CCDS52609.1
      UniProtKB/Swiss-Prot
      Q9CY27
      UniProtKB/TrEMBL
      G3UWE1
      Related
      ENSMUSP00000131389.2, ENSMUST00000165740.9
      Conserved Domains (2) summary
      PLN02560
      Location:38290
      PLN02560; enoyl-CoA reductase
      cl28922
      Location:366
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    2. NM_134118.5NP_598879.1  very-long-chain enoyl-CoA reductase isoform 1

      See identical proteins and their annotated locations for NP_598879.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK010984, BE994003, BY278351
      Consensus CDS
      CCDS40403.1
      UniProtKB/Swiss-Prot
      Q9CY27
      Related
      ENSMUSP00000019382.10, ENSMUST00000019382.17
      Conserved Domains (1) summary
      PLN02560
      Location:23305
      PLN02560; enoyl-CoA reductase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      84298327..84321120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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