U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SORBS1 sorbin and SH3 domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 10580, updated on 7-Apr-2024

    Summary

    Official Symbol
    SORBS1provided by HGNC
    Official Full Name
    sorbin and SH3 domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:14565
    See related
    Ensembl:ENSG00000095637 MIM:605264; AllianceGenome:HGNC:14565
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CAP; FLAF2; R85FL; SH3D5; SORB1; SH3P12
    Summary
    This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
    Expression
    Broad expression in fat (RPKM 111.7), heart (RPKM 81.6) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SORBS1 in Genome Data Viewer
    Location:
    10q24.1
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (95311773..95561371, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (96190944..96440561, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (97071530..97321128, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984257 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:96961907-96962201 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:96987152-96987893 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:96988638-96989207 Neighboring gene Sharpr-MPRA regulatory region 8644 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr10:96990347-96990915 and GRCh37_chr10:96990916-96991485 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:97000971-97001634 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97001635-97002298 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3792 Neighboring gene acyl-CoA synthetase medium chain family member 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3793 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:97020155-97020844 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97024067-97024842 Neighboring gene PDZ and LIM domain 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3794 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2640 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2641 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2642 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2643 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2644 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3795 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97054719-97055315 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3797 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3798 Neighboring gene CRISPRi-validated cis-regulatory element chr10.3436 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3799 Neighboring gene Sharpr-MPRA regulatory region 12220 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97106670-97107322 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2645 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2646 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3800 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:97190228-97190728 Neighboring gene Sharpr-MPRA regulatory region 10569 Neighboring gene VISTA enhancer hs2353 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:97291131-97291878 Neighboring gene NANOG hESC enhancer GRCh37_chr10:97299485-97299986 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97311480-97312414 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:97320711-97321473 Neighboring gene Sharpr-MPRA regulatory region 13709 Neighboring gene Sharpr-MPRA regulatory region 3716 Neighboring gene RPS3A pseudogene 36 Neighboring gene aldehyde dehydrogenase 18 family member A1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2649

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association study of suicide attempts in mood disorder patients.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies new susceptibility loci for migraine.
    EBI GWAS Catalog
    Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog
    SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.
    EBI GWAS Catalog

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat Microarray analysis indicates HIV-1 Tat-induced downregulation of sorbin and SH3 domain containing 1 (SORBS1) in primary human brain microvascular endothelial cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ12406, KIAA1296, DKFZp451C066, DKFZp586P1422

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables actin binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables cytoskeletal protein binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables insulin receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor complex adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables signaling receptor complex adaptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell-matrix adhesion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cell-substrate adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cellular response to insulin stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in focal adhesion assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in insulin receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of glucose import ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of glycogen biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of insulin receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of lipid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of protein localization to plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in stress fiber assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in adherens junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cell-substrate junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell-substrate junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of flotillin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
     
    located_in membrane raft ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
     
    located_in stress fiber ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in zonula adherens TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    sorbin and SH3 domain-containing protein 1
    Names
    Fas-ligand associated factor 2
    SH3 domain protein 5
    c-Cbl associated protein
    ponsin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_034041.2 RefSeqGene

      Range
      5000..254598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001034954.3NP_001030126.2  sorbin and SH3 domain-containing protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS31255.1
      UniProtKB/Swiss-Prot
      A0AED4, A6NEK3, A6NID8, A6NJS4, A7MD40, D3DR42, O43857, Q5T923, Q5T924, Q5T927, Q5T928, Q5T929, Q5T930, Q5T931, Q5T932, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9BX66, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338
      Related
      ENSP00000360293.2, ENST00000371247.7
      Conserved Domains (4) summary
      cd11916
      Location:12331291
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:796850
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:870927
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:370411
      Sorb; Sorbin homologous domain
    2. NM_001034955.2NP_001030127.2  sorbin and SH3 domain-containing protein 1 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL158165
      Consensus CDS
      CCDS31254.1
      Related
      ENSP00000277982.5, ENST00000277982.9
      Conserved Domains (4) summary
      cd11916
      Location:10921150
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:818872
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:892949
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:370411
      Sorb; Sorbin homologous domain
    3. NM_001034956.2NP_001030128.2  sorbin and SH3 domain-containing protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL158165
      Consensus CDS
      CCDS31256.1
      UniProtKB/TrEMBL
      A0A3B3IT56
      Related
      ENSP00000360291.2, ENST00000371245.7
      Conserved Domains (4) summary
      cd11916
      Location:846904
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:647701
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:721778
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:301342
      Sorb; Sorbin homologous domain
    4. NM_001034957.3NP_001030129.2  sorbin and SH3 domain-containing protein 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (5) summary
      cd11916
      Location:681739
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:502556
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:576633
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      COG5665
      Location:41327
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      cl02617
      Location:206247
      Sorb; Sorbin homologous domain
    5. NM_001290294.2NP_001277223.2  sorbin and SH3 domain-containing protein 1 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS73169.1
      Related
      ENSP00000360271.3, ENST00000371227.8
      Conserved Domains (4) summary
      smart00459
      Location:367412
      Sorb; Sorbin homologous domain
      cd11916
      Location:12071265
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:750804
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:824881
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    6. NM_001290295.2NP_001277224.2  sorbin and SH3 domain-containing protein 1 isoform 9

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has multiple differences in the coding region but maintains the reading frame, compared to variant 3. The encoded protein (isoform 9) is shorter than isoform 3.
      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Related
      ENSP00000496969.2, ENST00000647619.2
      Conserved Domains (5) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:690748
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:511565
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:585642
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam15449
      Location:51209
      Retinal; Retinal protein
    7. NM_001290296.2NP_001277225.2  sorbin and SH3 domain-containing protein 1 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL158165
      Consensus CDS
      CCDS76327.1
      Related
      ENSP00000277984.4, ENST00000354106.7
    8. NM_001290297.3NP_001277226.2  sorbin and SH3 domain-containing protein 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS76326.1
      UniProtKB/TrEMBL
      A0A3B3IT56
      Conserved Domains (4) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:752810
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:573627
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:647704
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    9. NM_001290298.3NP_001277227.2  sorbin and SH3 domain-containing protein 1 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:787845
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:608662
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:682739
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:238279
      Sorb; Sorbin homologous domain
    10. NM_001377197.1NP_001364126.1  sorbin and SH3 domain-containing protein 1 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      A0A3B3IT56
      Conserved Domains (4) summary
      cd11916
      Location:889947
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:710764
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:784841
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:361402
      Sorb; Sorbin homologous domain
    11. NM_001377198.1NP_001364127.1  sorbin and SH3 domain-containing protein 1 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:866924
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:687741
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:761818
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:338379
      Sorb; Sorbin homologous domain
    12. NM_001377199.1NP_001364128.1  sorbin and SH3 domain-containing protein 1 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:845903
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:666720
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:740797
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:370411
      Sorb; Sorbin homologous domain
    13. NM_001377200.1NP_001364129.1  sorbin and SH3 domain-containing protein 1 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:841899
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:662716
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:736793
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:338379
      Sorb; Sorbin homologous domain
    14. NM_001377201.1NP_001364130.1  sorbin and SH3 domain-containing protein 1 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:836894
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:657711
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:731788
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:361402
      Sorb; Sorbin homologous domain
    15. NM_001377202.1NP_001364131.1  sorbin and SH3 domain-containing protein 1 isoform 18

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:804862
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:625679
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:699756
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:329370
      Sorb; Sorbin homologous domain
    16. NM_001377203.1NP_001364132.1  sorbin and SH3 domain-containing protein 1 isoform 19

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:775833
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:596650
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:670727
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    17. NM_001377204.1NP_001364133.1  sorbin and SH3 domain-containing protein 1 isoform 20

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      A0A3B3IT56
      Conserved Domains (4) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:774832
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:595649
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:669726
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    18. NM_001377205.1NP_001364134.1  sorbin and SH3 domain-containing protein 1 isoform 21

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:766824
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:587641
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:661718
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:238279
      Sorb; Sorbin homologous domain
    19. NM_001377206.1NP_001364135.1  sorbin and SH3 domain-containing protein 1 isoform 22

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:750808
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:571625
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:645702
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    20. NM_001377207.1NP_001364136.1  sorbin and SH3 domain-containing protein 1 isoform 23

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:743801
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:564618
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:638695
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:215256
      Sorb; Sorbin homologous domain
    21. NM_001377208.1NP_001364137.1  sorbin and SH3 domain-containing protein 1 isoform 24

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:719777
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:540594
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:614671
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    22. NM_001377209.1NP_001364138.1  sorbin and SH3 domain-containing protein 1 isoform 25

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:718776
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:539593
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:613670
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:215256
      Sorb; Sorbin homologous domain
    23. NM_001384447.1NP_001371376.1  sorbin and SH3 domain-containing protein 1 isoform 26

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:15471605
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10661120
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11401197
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    24. NM_001384448.1NP_001371377.1  sorbin and SH3 domain-containing protein 1 isoform 27

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      A0A3B3IRW8
      Related
      ENSP00000497106.2, ENST00000649575.2
      Conserved Domains (5) summary
      cd11916
      Location:15601618
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10791133
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11531210
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      COG5665
      Location:41327
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam02208
      Location:206247
      Sorb; Sorbin homologous domain
    25. NM_001384449.1NP_001371378.1  sorbin and SH3 domain-containing protein 1 isoform 28

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:15251583
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10881142
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11621219
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    26. NM_001384450.1NP_001371379.1  sorbin and SH3 domain-containing protein 1 isoform 29

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:15031561
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10661120
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11401197
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    27. NM_001384451.1NP_001371380.1  sorbin and SH3 domain-containing protein 1 isoform 30

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Related
      ENSP00000475901.1, ENST00000607232.5
      Conserved Domains (4) summary
      cd11916
      Location:12451303
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10661120
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11401197
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    28. NM_001384452.1NP_001371381.1  sorbin and SH3 domain-containing protein 1 isoform 31

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:15691627
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10881142
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11621219
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    29. NM_001384453.1NP_001371382.1  sorbin and SH3 domain-containing protein 1 isoform 32

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:12671325
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10881142
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11621219
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    30. NM_001384454.1NP_001371383.1  sorbin and SH3 domain-containing protein 1 isoform 32

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Conserved Domains (4) summary
      cd11916
      Location:12671325
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:10881142
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:11621219
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:215256
      Sorb; Sorbin homologous domain
    31. NM_001384455.1NP_001371384.1  sorbin and SH3 domain-containing protein 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS76326.1
      UniProtKB/TrEMBL
      A0A3B3IT56
      Related
      ENSP00000360283.1, ENST00000371239.5
      Conserved Domains (4) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:752810
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:573627
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:647704
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    32. NM_001384456.1NP_001371385.1  sorbin and SH3 domain-containing protein 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS76326.1
      UniProtKB/TrEMBL
      A0A3B3IT56
      Conserved Domains (4) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:752810
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:573627
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:647704
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    33. NM_001384457.1NP_001371386.1  sorbin and SH3 domain-containing protein 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS76326.1
      UniProtKB/TrEMBL
      A0A3B3IT56
      Related
      ENSP00000497554.2, ENST00000649911.2
      Conserved Domains (4) summary
      smart00459
      Location:212257
      Sorb; Sorbin homologous domain
      cd11916
      Location:752810
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:573627
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:647704
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    34. NM_001384458.1NP_001371387.1  sorbin and SH3 domain-containing protein 1 isoform 33

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      A0A3B3IT56
      Conserved Domains (4) summary
      cd11916
      Location:842900
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:663717
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:737794
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:215256
      Sorb; Sorbin homologous domain
    35. NM_001384459.1NP_001371388.1  sorbin and SH3 domain-containing protein 1 isoform 34

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:839897
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:660714
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:734791
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    36. NM_001384460.1NP_001371389.1  sorbin and SH3 domain-containing protein 1 isoform 35

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:818876
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:639693
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:713770
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    37. NM_001384461.1NP_001371390.1  sorbin and SH3 domain-containing protein 1 isoform 36

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:786844
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:607661
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:681738
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:215256
      Sorb; Sorbin homologous domain
    38. NM_001384462.1NP_001371391.1  sorbin and SH3 domain-containing protein 1 isoform 37

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:777835
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:598652
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:672729
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:206247
      Sorb; Sorbin homologous domain
    39. NM_001384463.1NP_001371392.1  sorbin and SH3 domain-containing protein 1 isoform 38

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:709767
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:530584
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:604661
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:247288
      Sorb; Sorbin homologous domain
    40. NM_001384464.1NP_001371393.1  sorbin and SH3 domain-containing protein 1 isoform 39

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:705763
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:526580
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:600657
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:215256
      Sorb; Sorbin homologous domain
    41. NM_001384465.1NP_001371394.1  sorbin and SH3 domain-containing protein 1 isoform 40

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      UniProtKB/TrEMBL
      B4DTX5
      Conserved Domains (4) summary
      cd11916
      Location:774832
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:595649
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:669726
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:238279
      Sorb; Sorbin homologous domain
    42. NM_001419685.1NP_001406614.1  sorbin and SH3 domain-containing protein 1 isoform 41

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
    43. NM_001419702.1NP_001406631.1  sorbin and SH3 domain-containing protein 1 isoform 42

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
    44. NM_001419703.1NP_001406632.1  sorbin and SH3 domain-containing protein 1 isoform 43

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
    45. NM_001419704.1NP_001406633.1  sorbin and SH3 domain-containing protein 1 isoform 44

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
    46. NM_006434.4NP_006425.3  sorbin and SH3 domain-containing protein 1 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS31252.1
      UniProtKB/TrEMBL
      B4DTX5
      Related
      ENSP00000360285.1, ENST00000371241.5
    47. NM_015385.4NP_056200.2  sorbin and SH3 domain-containing protein 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS7442.1
      UniProtKB/TrEMBL
      B4DTX5
      Related
      ENSP00000360295.2, ENST00000371249.6
      Conserved Domains (4) summary
      smart00459
      Location:335380
      Sorb; Sorbin homologous domain
      cd11916
      Location:757815
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:578632
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:652709
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    48. NM_024991.3NP_079267.2  sorbin and SH3 domain-containing protein 1 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL157890, AL158165
      Consensus CDS
      CCDS31253.1
      UniProtKB/TrEMBL
      B4DTX5
      Related
      ENSP00000302556.6, ENST00000306402.10
      Conserved Domains (5) summary
      smart00459
      Location:244289
      Sorb; Sorbin homologous domain
      cd11916
      Location:722780
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:543597
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:617674
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam15449
      Location:83241
      Retinal; Retinal protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      95311773..95561371 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015539.2XP_016871028.1  sorbin and SH3 domain-containing protein 1 isoform X27

      UniProtKB/TrEMBL
      B4DTX5
    2. XM_017015540.2XP_016871029.1  sorbin and SH3 domain-containing protein 1 isoform X28

      UniProtKB/TrEMBL
      B4DTX5
    3. XM_017015533.2XP_016871022.1  sorbin and SH3 domain-containing protein 1 isoform X23

      UniProtKB/TrEMBL
      B4DTX5
    4. XM_047424475.1XP_047280431.1  sorbin and SH3 domain-containing protein 1 isoform X20

    5. XM_047424471.1XP_047280427.1  sorbin and SH3 domain-containing protein 1 isoform X14

    6. XM_047424470.1XP_047280426.1  sorbin and SH3 domain-containing protein 1 isoform X13

    7. XM_047424479.1XP_047280435.1  sorbin and SH3 domain-containing protein 1 isoform X31

    8. XM_017015536.2XP_016871025.1  sorbin and SH3 domain-containing protein 1 isoform X24

      UniProtKB/TrEMBL
      B4DTX5
    9. XM_017015525.2XP_016871014.1  sorbin and SH3 domain-containing protein 1 isoform X16

      UniProtKB/TrEMBL
      A0A3B3IT56
    10. XM_017015523.2XP_016871012.1  sorbin and SH3 domain-containing protein 1 isoform X15

      UniProtKB/TrEMBL
      B4DTX5
    11. XM_047424473.1XP_047280429.1  sorbin and SH3 domain-containing protein 1 isoform X18

    12. XM_047424478.1XP_047280434.1  sorbin and SH3 domain-containing protein 1 isoform X30

    13. XM_017015537.3XP_016871026.1  sorbin and SH3 domain-containing protein 1 isoform X25

      UniProtKB/TrEMBL
      B4DTX5
    14. XM_017015532.3XP_016871021.1  sorbin and SH3 domain-containing protein 1 isoform X22

      UniProtKB/TrEMBL
      B4DTX5
    15. XM_047424476.1XP_047280432.1  sorbin and SH3 domain-containing protein 1 isoform X26

    16. XM_047424474.1XP_047280430.1  sorbin and SH3 domain-containing protein 1 isoform X19

    17. XM_006717589.3XP_006717652.1  sorbin and SH3 domain-containing protein 1 isoform X9

      UniProtKB/Swiss-Prot
      Q9BX66
      Conserved Domains (4) summary
      cd11916
      Location:9451003
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:766820
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:840897
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:361399
      Sorb; Sorbin homologous domain
    18. XM_047424477.1XP_047280433.1  sorbin and SH3 domain-containing protein 1 isoform X29

    19. XM_017015530.3XP_016871019.1  sorbin and SH3 domain-containing protein 1 isoform X21

      UniProtKB/TrEMBL
      B4DTX5
    20. XM_047424472.1XP_047280428.1  sorbin and SH3 domain-containing protein 1 isoform X17

    21. XM_047424469.1XP_047280425.1  sorbin and SH3 domain-containing protein 1 isoform X11

    22. XM_017015517.3XP_016871006.1  sorbin and SH3 domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      B4DTX5
    23. XM_017015515.3XP_016871004.1  sorbin and SH3 domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A3B3IT56
    24. XM_017015510.3XP_016870999.1  sorbin and SH3 domain-containing protein 1 isoform X8

    25. XM_017015505.3XP_016870994.1  sorbin and SH3 domain-containing protein 1 isoform X5

    26. XM_047424468.1XP_047280424.1  sorbin and SH3 domain-containing protein 1 isoform X7

    27. XM_017015503.3XP_016870992.1  sorbin and SH3 domain-containing protein 1 isoform X4

    28. XM_017015501.3XP_016870990.1  sorbin and SH3 domain-containing protein 1 isoform X2

    29. XM_011539150.3XP_011537452.1  sorbin and SH3 domain-containing protein 1 isoform X1

      Conserved Domains (4) summary
      cd11916
      Location:14461504
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:9891043
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:10631120
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:609650
      Sorb; Sorbin homologous domain
    30. XM_017015507.3XP_016870996.1  sorbin and SH3 domain-containing protein 1 isoform X6

    31. XM_017015502.3XP_016870991.1  sorbin and SH3 domain-containing protein 1 isoform X3

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      96190944..96440561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054364574.1XP_054220549.1  sorbin and SH3 domain-containing protein 1 isoform X27

    2. XM_054364575.1XP_054220550.1  sorbin and SH3 domain-containing protein 1 isoform X28

    3. XM_054364570.1XP_054220545.1  sorbin and SH3 domain-containing protein 1 isoform X23

    4. XM_054364567.1XP_054220542.1  sorbin and SH3 domain-containing protein 1 isoform X20

    5. XM_054364561.1XP_054220536.1  sorbin and SH3 domain-containing protein 1 isoform X14

    6. XM_054364560.1XP_054220535.1  sorbin and SH3 domain-containing protein 1 isoform X13

    7. XM_054364578.1XP_054220553.1  sorbin and SH3 domain-containing protein 1 isoform X31

    8. XM_054364571.1XP_054220546.1  sorbin and SH3 domain-containing protein 1 isoform X24

    9. XM_054364563.1XP_054220538.1  sorbin and SH3 domain-containing protein 1 isoform X16

    10. XM_054364562.1XP_054220537.1  sorbin and SH3 domain-containing protein 1 isoform X15

    11. XM_054364565.1XP_054220540.1  sorbin and SH3 domain-containing protein 1 isoform X18

    12. XM_054364577.1XP_054220552.1  sorbin and SH3 domain-containing protein 1 isoform X30

    13. XM_054364572.1XP_054220547.1  sorbin and SH3 domain-containing protein 1 isoform X25

    14. XM_054364569.1XP_054220544.1  sorbin and SH3 domain-containing protein 1 isoform X22

    15. XM_054364573.1XP_054220548.1  sorbin and SH3 domain-containing protein 1 isoform X26

    16. XM_054364566.1XP_054220541.1  sorbin and SH3 domain-containing protein 1 isoform X19

    17. XM_054364556.1XP_054220531.1  sorbin and SH3 domain-containing protein 1 isoform X9

    18. XM_054364576.1XP_054220551.1  sorbin and SH3 domain-containing protein 1 isoform X29

    19. XM_054364568.1XP_054220543.1  sorbin and SH3 domain-containing protein 1 isoform X21

    20. XM_054364564.1XP_054220539.1  sorbin and SH3 domain-containing protein 1 isoform X17

    21. XM_054364558.1XP_054220533.1  sorbin and SH3 domain-containing protein 1 isoform X11

    22. XM_054364559.1XP_054220534.1  sorbin and SH3 domain-containing protein 1 isoform X12

    23. XM_054364557.1XP_054220532.1  sorbin and SH3 domain-containing protein 1 isoform X10

    24. XM_054364555.1XP_054220530.1  sorbin and SH3 domain-containing protein 1 isoform X8

    25. XM_054364552.1XP_054220527.1  sorbin and SH3 domain-containing protein 1 isoform X5

    26. XM_054364554.1XP_054220529.1  sorbin and SH3 domain-containing protein 1 isoform X7

    27. XM_054364551.1XP_054220526.1  sorbin and SH3 domain-containing protein 1 isoform X4

    28. XM_054364549.1XP_054220524.1  sorbin and SH3 domain-containing protein 1 isoform X2

    29. XM_054364548.1XP_054220523.1  sorbin and SH3 domain-containing protein 1 isoform X1

    30. XM_054364553.1XP_054220528.1  sorbin and SH3 domain-containing protein 1 isoform X6

    31. XM_054364550.1XP_054220525.1  sorbin and SH3 domain-containing protein 1 isoform X3