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    Mycbp2 MYC binding protein 2, E3 ubiquitin protein ligase [ Mus musculus (house mouse) ]

    Gene ID: 105689, updated on 4-Jul-2021

    Summary

    Official Symbol
    Mycbp2provided by MGI
    Official Full Name
    MYC binding protein 2, E3 ubiquitin protein ligaseprovided by MGI
    Primary source
    MGI:MGI:2179432
    See related
    Ensembl:ENSMUSG00000033004
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; Ph; Pam; Phr1; R75243; AU023734; AW107953; AW546647; C130061D10Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 20.7), cerebellum adult (RPKM 15.2) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mycbp2 in Genome Data Viewer
    Location:
    14 E2.3; 14 51.79 cM
    Exon count:
    88
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (103350847..103584276, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (103113411..103346840, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (103512628..103746017, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ceroid-lipofuscinosis, neuronal 5 Neighboring gene F-box and leucine-rich repeat protein 3 Neighboring gene predicted gene, 34758 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within branchiomotor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cell morphogenesis involved in neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within central nervous system projection neuron axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in central nervous system projection neuron axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in circadian regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in circadian regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in neuromuscular process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase MYCBP2
    Names
    Myc-binding protein 2
    RING-type E3 ubiquitin transferase MYCBP2
    pam, highwire, rpm 1
    pam/highwire/rpm-1 protein
    probable E3 ubiquitin-protein ligase MYCBP2
    protein Magellan
    protein associated with Myc
    NP_997098.2
    XP_006518455.1
    XP_011243195.1
    XP_011243196.1
    XP_011243197.1
    XP_011243198.1
    XP_011243199.1
    XP_011243200.1
    XP_011243201.1
    XP_011243202.1
    XP_011243203.1
    XP_011243204.1
    XP_011243205.1
    XP_011243206.1
    XP_011243207.1
    XP_011243208.1
    XP_011243209.1
    XP_017171266.1
    XP_017171267.1
    XP_017171268.1
    XP_017171269.1
    XP_017171271.1
    XP_017171272.1
    XP_017171273.1
    XP_017171274.1
    XP_017171275.1
    XP_017171276.1
    XP_017171277.1
    XP_017171278.1
    XP_017171279.1
    XP_017171280.1
    XP_017171281.1
    XP_017171282.1
    XP_017171283.1
    XP_030103457.1
    XP_030103458.1
    XP_030103459.1
    XP_030103460.1
    XP_030103461.1
    XP_036014271.1
    XP_036014272.1
    XP_036014273.1
    XP_036014275.1
    XP_036014276.1
    XP_036014278.1
    XP_036014279.1
    XP_036014280.1
    XP_036014281.1
    XP_036014282.1
    XP_036014283.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207215.2NP_997098.2  E3 ubiquitin-protein ligase MYCBP2

      Status: VALIDATED

      Source sequence(s)
      AC114410, AC114585, AY325887, BC059257
      Consensus CDS
      CCDS49559.1
      UniProtKB/Swiss-Prot
      Q7TPH6
      UniProtKB/TrEMBL
      E9PUJ6
      Related
      ENSMUSP00000124710.2, ENSMUST00000159855.8
      Conserved Domains (6) summary
      smart00557
      Location:23892440
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17241879
      PHR; PHR domain
      pfam13540
      Location:943971
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:44944547
      zf-RING_2; Ring finger domain
      cl02148
      Location:38193911
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      103350847..103584276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158378.1XP_036014271.1  E3 ubiquitin-protein ligase MYCBP2 isoform X7

      Conserved Domains (9) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45394593
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:43734421
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38623954
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:12351385
      PHR; PHR domain
      pfam08239
      Location:24722534
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:23892440
      Filamin; Filamin/ABP280 repeat
    2. XM_011244896.3XP_011243198.1  E3 ubiquitin-protein ligase MYCBP2 isoform X5

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45414595
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17261881
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43754423
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38643956
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23912442
      Filamin; Filamin/ABP280 repeat
    3. XM_017315794.2XP_017171283.1  E3 ubiquitin-protein ligase MYCBP2 isoform X47

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43454399
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:41794227
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:36713763
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    4. XM_017315789.2XP_017171278.1  E3 ubiquitin-protein ligase MYCBP2 isoform X33

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44004454
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42344282
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37233815
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    5. XM_011244906.3XP_011243208.1  E3 ubiquitin-protein ligase MYCBP2 isoform X30

      Related
      ENSMUSP00000124601.2, ENSMUST00000160758.8
      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44234477
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42574305
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37463838
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    6. XM_017315783.2XP_017171272.1  E3 ubiquitin-protein ligase MYCBP2 isoform X21

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44754529
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43094357
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37983890
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    7. XM_036158379.1XP_036014272.1  E3 ubiquitin-protein ligase MYCBP2 isoform X12

      Conserved Domains (9) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45094563
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:43434391
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38323924
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:12351385
      PHR; PHR domain
      pfam08239
      Location:24752537
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    8. XM_030247598.1XP_030103458.1  E3 ubiquitin-protein ligase MYCBP2 isoform X26

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44484502
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42824330
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37713863
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    9. XM_036158380.1XP_036014273.1  E3 ubiquitin-protein ligase MYCBP2 isoform X19

      Conserved Domains (9) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44824536
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:43164364
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38053897
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:12351385
      PHR; PHR domain
      pfam08239
      Location:24752537
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    10. XM_017315779.2XP_017171268.1  E3 ubiquitin-protein ligase MYCBP2 isoform X16

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45004554
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43344382
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38233915
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    11. XM_011244895.3XP_011243197.1  E3 ubiquitin-protein ligase MYCBP2 isoform X3

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45424596
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17271882
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43764424
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38653957
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23922443
      Filamin; Filamin/ABP280 repeat
    12. XM_017315793.2XP_017171282.1  E3 ubiquitin-protein ligase MYCBP2 isoform X39

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43474401
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:41814229
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:36733765
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    13. XM_017315792.2XP_017171281.1  E3 ubiquitin-protein ligase MYCBP2 isoform X38

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43504404
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:41844232
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:36733765
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    14. XM_030247599.1XP_030103459.1  E3 ubiquitin-protein ligase MYCBP2 isoform X35

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43844438
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42184266
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37073799
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    15. XM_017315788.2XP_017171277.1  E3 ubiquitin-protein ligase MYCBP2 isoform X32

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44024456
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42364284
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37253817
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    16. XM_017315787.2XP_017171276.1  E3 ubiquitin-protein ligase MYCBP2 isoform X28

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44364490
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42704318
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37593851
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    17. XM_036158382.1XP_036014275.1  E3 ubiquitin-protein ligase MYCBP2 isoform X31

      Conserved Domains (9) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44104464
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:42444292
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37333825
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:12351385
      PHR; PHR domain
      pfam08239
      Location:24772539
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    18. XM_011244904.3XP_011243206.1  E3 ubiquitin-protein ligase MYCBP2 isoform X27

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44444498
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42784326
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37673859
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    19. XM_011244905.3XP_011243207.1  E3 ubiquitin-protein ligase MYCBP2 isoform X29

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44254479
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42594307
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37483840
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    20. XM_017315786.2XP_017171275.1  E3 ubiquitin-protein ligase MYCBP2 isoform X24

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44594513
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42934341
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37823874
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    21. XM_011244902.3XP_011243204.1  E3 ubiquitin-protein ligase MYCBP2 isoform X20

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44774531
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43114359
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38003892
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    22. XM_030247597.1XP_030103457.1  E3 ubiquitin-protein ligase MYCBP2 isoform X10

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45114565
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43454393
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38343926
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    23. XM_011244898.3XP_011243200.1  E3 ubiquitin-protein ligase MYCBP2 isoform X9

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45194573
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43534401
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38423934
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    24. XM_011244903.3XP_011243205.1  E3 ubiquitin-protein ligase MYCBP2 isoform X25

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44504504
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:42844332
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37733865
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    25. XM_017315782.2XP_017171271.1  E3 ubiquitin-protein ligase MYCBP2 isoform X18

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44844538
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43184366
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38073899
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    26. XM_017315780.2XP_017171269.1  E3 ubiquitin-protein ligase MYCBP2 isoform X17

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44994553
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43334381
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38253917
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    27. XM_011244901.3XP_011243203.1  E3 ubiquitin-protein ligase MYCBP2 isoform X15

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45024556
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43364384
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38253917
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    28. XM_011244897.3XP_011243199.1  E3 ubiquitin-protein ligase MYCBP2 isoform X8

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45364590
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43704418
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38593951
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    29. XM_011244899.3XP_011243201.1  E3 ubiquitin-protein ligase MYCBP2 isoform X11

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45104564
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43444392
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38333925
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    30. XM_017315777.2XP_017171266.1  E3 ubiquitin-protein ligase MYCBP2 isoform X6

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45404594
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43744422
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38663958
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    31. XM_011244894.3XP_011243196.1  E3 ubiquitin-protein ligase MYCBP2 isoform X2

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45434597
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43774425
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38663958
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    32. XM_006518392.3XP_006518455.1  E3 ubiquitin-protein ligase MYCBP2 isoform X4

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45414595
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43754423
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38673959
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    33. XM_011244893.3XP_011243195.1  E3 ubiquitin-protein ligase MYCBP2 isoform X1

      Conserved Domains (8) summary
      COG5184
      Location:9061026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45444598
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:9581006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:17291884
      PHR; PHR domain
      pfam13540
      Location:683712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:43784426
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38673959
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23942445
      Filamin; Filamin/ABP280 repeat
    34. XM_017315785.2XP_017171274.1  E3 ubiquitin-protein ligase MYCBP2 isoform X23

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44614515
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16881843
      PHR; PHR domain
      cd19799
      Location:42954343
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37843876
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23532404
      Filamin; Filamin/ABP280 repeat
    35. XM_017315791.2XP_017171280.1  E3 ubiquitin-protein ligase MYCBP2 isoform X37

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43644418
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16911846
      PHR; PHR domain
      cd19799
      Location:41984246
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:36873779
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23562407
      Filamin; Filamin/ABP280 repeat
    36. XM_036158383.1XP_036014276.1  E3 ubiquitin-protein ligase MYCBP2 isoform X34

      Conserved Domains (8) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43874441
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:42214269
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37103802
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:11991349
      PHR; PHR domain
      pfam08239
      Location:24392501
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:23562407
      Filamin; Filamin/ABP280 repeat
    37. XM_017315784.2XP_017171273.1  E3 ubiquitin-protein ligase MYCBP2 isoform X22

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:44644518
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16911846
      PHR; PHR domain
      cd19799
      Location:42984346
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:37873879
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23562407
      Filamin; Filamin/ABP280 repeat
    38. XM_017315778.2XP_017171267.1  E3 ubiquitin-protein ligase MYCBP2 isoform X14

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45064560
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16911846
      PHR; PHR domain
      cd19799
      Location:43404388
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38293921
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23562407
      Filamin; Filamin/ABP280 repeat
    39. XM_017315790.2XP_017171279.1  E3 ubiquitin-protein ligase MYCBP2 isoform X36

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:43664420
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16931848
      PHR; PHR domain
      cd19799
      Location:42004248
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:36893781
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23582409
      Filamin; Filamin/ABP280 repeat
    40. XM_011244900.3XP_011243202.1  E3 ubiquitin-protein ligase MYCBP2 isoform X13

      Conserved Domains (7) summary
      COG5184
      Location:683988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:45084562
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:16931848
      PHR; PHR domain
      cd19799
      Location:43424390
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:38313923
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:23582409
      Filamin; Filamin/ABP280 repeat
    41. XM_030247601.1XP_030103461.1  E3 ubiquitin-protein ligase MYCBP2 isoform X41

      Conserved Domains (8) summary
      cd16463
      Location:35873641
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:351
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:772927
      PHR; PHR domain
      pfam08239
      Location:15201582
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:3967
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:34213469
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:29103002
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:14371488
      Filamin; Filamin/ABP280 repeat
    42. XM_011244907.3XP_011243209.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      Conserved Domains (8) summary
      cd16463
      Location:35893643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:34233471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:29123004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:351
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280430
      PHR; PHR domain
      pfam08239
      Location:15221584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:3967
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:14391490
      Filamin; Filamin/ABP280 repeat
    43. XM_036158385.1XP_036014278.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      Conserved Domains (8) summary
      cd16463
      Location:35893643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:34233471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:29123004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:351
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280430
      PHR; PHR domain
      pfam08239
      Location:15221584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:3967
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:14391490
      Filamin; Filamin/ABP280 repeat
    44. XM_030247600.2XP_030103460.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      Conserved Domains (8) summary
      cd16463
      Location:35893643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:34233471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:29123004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:351
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280430
      PHR; PHR domain
      pfam08239
      Location:15221584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:3967
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:14391490
      Filamin; Filamin/ABP280 repeat
    45. XM_036158388.1XP_036014281.1  E3 ubiquitin-protein ligase MYCBP2 isoform X44

      Conserved Domains (6) summary
      cd16463
      Location:28802934
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:27142762
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:22032295
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72229
      PHR; PHR domain
      pfam08239
      Location:821883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738789
      Filamin; Filamin/ABP280 repeat
    46. XM_036158389.1XP_036014282.1  E3 ubiquitin-protein ligase MYCBP2 isoform X45

      Conserved Domains (6) summary
      cd16463
      Location:28212875
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:26552703
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:21442236
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72229
      PHR; PHR domain
      pfam08239
      Location:821883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738789
      Filamin; Filamin/ABP280 repeat
    47. XM_036158390.1XP_036014283.1  E3 ubiquitin-protein ligase MYCBP2 isoform X46

      Conserved Domains (6) summary
      cd16463
      Location:27942848
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:26282676
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:21172209
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72229
      PHR; PHR domain
      pfam08239
      Location:821883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738789
      Filamin; Filamin/ABP280 repeat
    48. XM_036158387.1XP_036014280.1  E3 ubiquitin-protein ligase MYCBP2 isoform X43

      Conserved Domains (6) summary
      cd16463
      Location:28882942
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:27222770
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:22112303
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72229
      PHR; PHR domain
      pfam08239
      Location:821883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738789
      Filamin; Filamin/ABP280 repeat
    49. XM_036158386.1XP_036014279.1  E3 ubiquitin-protein ligase MYCBP2 isoform X42

      Conserved Domains (6) summary
      cd16463
      Location:28902944
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:27242772
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:22132305
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:74231
      PHR; PHR domain
      pfam08239
      Location:823885
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:740791
      Filamin; Filamin/ABP280 repeat
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