U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Slain1 SLAIN motif family, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 105439, updated on 17-Aug-2024

    Summary

    Official Symbol
    Slain1provided by MGI
    Official Full Name
    SLAIN motif family, member 1provided by MGI
    Primary source
    MGI:MGI:2145578
    See related
    Ensembl:ENSMUSG00000055717 AllianceGenome:MGI:2145578
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630044O09Rik
    Summary
    Predicted to be involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to colocalize with microtubule plus-end. Is expressed in several structures, including brain; immune system; neural ectoderm; sensory organ; and somite. Orthologous to human SLAIN1 (SLAIN motif family member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 21.4), whole brain E14.5 (RPKM 19.0) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slain1 in Genome Data Viewer
    Location:
    14 E2.3; 14 52.75 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (103887664..103942343)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (103650228..103704907)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10840 Neighboring gene STARR-positive B cell enhancer ABC_E5464 Neighboring gene predicted gene, 34907 Neighboring gene STARR-seq mESC enhancer starr_37505 Neighboring gene sciellin Neighboring gene STARR-seq mESC enhancer starr_37506 Neighboring gene STARR-seq mESC enhancer starr_37507 Neighboring gene STARR-positive B cell enhancer ABC_E10841 Neighboring gene STARR-seq mESC enhancer starr_37509 Neighboring gene SLAIN motif family, member 1, opposite strand Neighboring gene STARR-seq mESC enhancer starr_37510 Neighboring gene predicted gene, 35197 Neighboring gene predicted gene, 35116 Neighboring gene STARR-seq mESC enhancer starr_37511 Neighboring gene endothelin receptor type B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of microtubule polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    SLAIN motif-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361639.1NP_001348568.1  SLAIN motif-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK036190, BC079866, BX529670
      UniProtKB/TrEMBL
      F7D4S5
      Related
      ENSMUSP00000125128.2, ENSMUST00000160805.8
      Conserved Domains (1) summary
      pfam15301
      Location:185629
      SLAIN; SLAIN motif-containing family
    2. NM_198014.3NP_932131.2  SLAIN motif-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_932131.2

      Status: VALIDATED

      Source sequence(s)
      AK036190, BC079866, BX529670
      Consensus CDS
      CCDS27316.1
      UniProtKB/Swiss-Prot
      Q68FF7, Q8R3I6
      UniProtKB/TrEMBL
      F7D4S5
      Related
      ENSMUSP00000070592.8, ENSMUST00000069443.14
      Conserved Domains (1) summary
      pfam15301
      Location:185579
      SLAIN; SLAIN motif-containing family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      103887664..103942343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)