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    Brd9 bromodomain containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 105246, updated on 23-Jun-2021

    Summary

    Official Symbol
    Brd9provided by MGI
    Official Full Name
    bromodomain containing 9provided by MGI
    Primary source
    MGI:MGI:2145317
    See related
    Ensembl:ENSMUSG00000057649
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AL022779
    Expression
    Ubiquitous expression in CNS E14 (RPKM 20.2), CNS E18 (RPKM 19.3) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Brd9 in Genome Data Viewer
    Location:
    13; 13 C1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74085920..74109014)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (73937801..73960895)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (74075286..74098343)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30432 Neighboring gene thyroid hormone receptor interactor 13 Neighboring gene U7 small nuclear RNA Neighboring gene predicted gene, 41002 Neighboring gene zinc finger, DHHC domain containing 11 Neighboring gene ribosomal protein S29 pseudogene Neighboring gene predicted gene 15912

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lysine-acetylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables lysine-acetylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    bromodomain-containing protein 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024508.4NP_001019679.2  bromodomain-containing protein 9 isoform 1

      See identical proteins and their annotated locations for NP_001019679.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      CT010471
      Consensus CDS
      CCDS36728.1
      UniProtKB/Swiss-Prot
      Q3UQU0
      UniProtKB/TrEMBL
      A0A0R4J175
      Related
      ENSMUSP00000096982.3, ENSMUST00000099384.4
      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:274503
      DUF3512; Domain of unknown function (DUF3512)
    2. NM_001308041.2NP_001294970.1  bromodomain-containing protein 9 isoform 2

      See identical proteins and their annotated locations for NP_001294970.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is one amino acid shorter than isoform 1.
      Source sequence(s)
      CT010471
      Consensus CDS
      CCDS88482.1
      UniProtKB/Swiss-Prot
      Q3UQU0
      Related
      ENSMUSP00000152390.2, ENSMUST00000222399.2
      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:273502
      DUF3512; Domain of unknown function (DUF3512)
    3. NM_001378947.1NP_001365876.1  bromodomain-containing protein 9 isoform 3

      Status: VALIDATED

      Source sequence(s)
      CT010471
      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:306485
      DUF3512; Domain of unknown function (DUF3512)
    4. NM_001378948.1NP_001365877.1  bromodomain-containing protein 9 isoform 4

      Status: VALIDATED

      Source sequence(s)
      CT010471
      Conserved Domains (2) summary
      pfam12024
      Location:79258
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      74085920..74109014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247105.1XP_030102965.1  bromodomain-containing protein 9 isoform X2

      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:274461
      DUF3512; Domain of unknown function (DUF3512)
    2. XM_030247103.2XP_030102963.1  bromodomain-containing protein 9 isoform X1

      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:294481
      DUF3512; Domain of unknown function (DUF3512)
    3. XM_036157813.1XP_036013706.1  bromodomain-containing protein 9 isoform X6

      Conserved Domains (1) summary
      pfam12024
      Location:59238
      DUF3512; Domain of unknown function (DUF3512)
    4. XM_036157814.1XP_036013707.1  bromodomain-containing protein 9 isoform X7

      Conserved Domains (1) summary
      pfam12024
      Location:58237
      DUF3512; Domain of unknown function (DUF3512)
    5. XM_036157816.1XP_036013709.1  bromodomain-containing protein 9 isoform X8

      Conserved Domains (1) summary
      pfam12024
      Location:7186
      DUF3512; Domain of unknown function (DUF3512)
    6. XM_030247107.1XP_030102967.1  bromodomain-containing protein 9 isoform X5

      Related
      ENSMUST00000222191.2
      Conserved Domains (1) summary
      pfam12024
      Location:60239
      DUF3512; Domain of unknown function (DUF3512)
    7. XM_017315340.1XP_017170829.1  bromodomain-containing protein 9 isoform X3

      Conserved Domains (2) summary
      pfam12024
      Location:87316
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    8. XM_036157810.1XP_036013703.1  bromodomain-containing protein 9 isoform X4

      Related
      ENSMUST00000220488.2
      Conserved Domains (2) summary
      pfam12024
      Location:78257
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    9. XM_036157812.1XP_036013705.1  bromodomain-containing protein 9 isoform X5

      Conserved Domains (1) summary
      pfam12024
      Location:60239
      DUF3512; Domain of unknown function (DUF3512)
    10. XM_036157817.1XP_036013710.1  bromodomain-containing protein 9 isoform X8

      Conserved Domains (1) summary
      pfam12024
      Location:7186
      DUF3512; Domain of unknown function (DUF3512)
    11. XM_036157811.1XP_036013704.1  bromodomain-containing protein 9 isoform X4

      Conserved Domains (2) summary
      pfam12024
      Location:78257
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    12. XM_036157815.1XP_036013708.1  bromodomain-containing protein 9 isoform X7

      Conserved Domains (1) summary
      pfam12024
      Location:58237
      DUF3512; Domain of unknown function (DUF3512)
    13. XM_006517030.3XP_006517093.1  bromodomain-containing protein 9 isoform X5

      Conserved Domains (1) summary
      pfam12024
      Location:60239
      DUF3512; Domain of unknown function (DUF3512)
    14. XM_006517029.2XP_006517092.1  bromodomain-containing protein 9 isoform X3

      Conserved Domains (2) summary
      pfam12024
      Location:87316
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
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