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    Brd9 bromodomain containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 105246, updated on 31-Jan-2019

    Summary

    Official Symbol
    Brd9provided by MGI
    Official Full Name
    bromodomain containing 9provided by MGI
    Primary source
    MGI:MGI:2145317
    See related
    Ensembl:ENSMUSG00000057649
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AL022779
    Expression
    Ubiquitous expression in CNS E14 (RPKM 20.2), CNS E18 (RPKM 19.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Brd9 in Genome Data Viewer
    Location:
    13; 13 C1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (73937811..73960895)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (74075286..74098343)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30432 Neighboring gene thyroid hormone receptor interactor 13 Neighboring gene predicted gene, 41002 Neighboring gene zinc finger, DHHC domain containing 11 Neighboring gene ribosomal protein S29 pseudogene Neighboring gene tubulin polymerization promoting protein Neighboring gene integrin linked kinase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    lysine-acetylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    bromodomain-containing protein 9

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024508.3NP_001019679.2  bromodomain-containing protein 9 isoform 1

      See identical proteins and their annotated locations for NP_001019679.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK142152, BC089379, BY035489
      Consensus CDS
      CCDS36728.1
      UniProtKB/Swiss-Prot
      Q3UQU0
      UniProtKB/TrEMBL
      A0A0R4J175
      Related
      ENSMUSP00000096982.2, ENSMUST00000099384.3
      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:274503
      DUF3512; Domain of unknown function (DUF3512)
    2. NM_001308041.1NP_001294970.1  bromodomain-containing protein 9 isoform 2

      See identical proteins and their annotated locations for NP_001294970.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is one amino acid shorter than isoform 1.
      Source sequence(s)
      AK142152, BC089379, BY035489
      UniProtKB/Swiss-Prot
      Q3UQU0
      Related
      ENSMUSP00000152390.1, ENSMUST00000222399.1
      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:273502
      DUF3512; Domain of unknown function (DUF3512)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      73937811..73960895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517024.2XP_006517087.1  bromodomain-containing protein 9 isoform X2

      See identical proteins and their annotated locations for XP_006517087.1

      Conserved Domains (2) summary
      cd05513
      Location:140237
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:294523
      DUF3512; Domain of unknown function (DUF3512)
    2. XM_017315343.1XP_017170832.1  bromodomain-containing protein 9 isoform X8

    3. XM_017315345.1XP_017170834.1  bromodomain-containing protein 9 isoform X10

      Conserved Domains (1) summary
      pfam12024
      Location:47276
      DUF3512; Domain of unknown function (DUF3512)
    4. XM_017315347.1XP_017170836.1  bromodomain-containing protein 9 isoform X11

    5. XM_017315340.1XP_017170829.1  bromodomain-containing protein 9 isoform X6

      Conserved Domains (2) summary
      pfam12024
      Location:87316
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    6. XM_017315341.1XP_017170830.1  bromodomain-containing protein 9 isoform X7

    7. XM_017315339.1XP_017170828.1  bromodomain-containing protein 9 isoform X5

    8. XM_017315337.1XP_017170826.1  bromodomain-containing protein 9 isoform X1

    9. XM_006517026.2XP_006517089.1  bromodomain-containing protein 9 isoform X4

      Conserved Domains (2) summary
      cd05513
      Location:149246
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:282511
      DUF3512; Domain of unknown function (DUF3512)
    10. XM_017315338.1XP_017170827.1  bromodomain-containing protein 9 isoform X3

    11. XM_006517030.3XP_006517093.1  bromodomain-containing protein 9 isoform X9

      Conserved Domains (1) summary
      pfam12024
      Location:48277
      DUF3512; Domain of unknown function (DUF3512)
    12. XM_006517029.2XP_006517092.1  bromodomain-containing protein 9 isoform X6

      Conserved Domains (2) summary
      pfam12024
      Location:87316
      DUF3512; Domain of unknown function (DUF3512)
      cl02556
      Location:130
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    13. XM_017315342.1XP_017170831.1  bromodomain-containing protein 9 isoform X7

    14. XM_017315344.1XP_017170833.1  bromodomain-containing protein 9 isoform X8

    15. XM_006517031.3XP_006517094.1  bromodomain-containing protein 9 isoform X10

      Conserved Domains (1) summary
      pfam12024
      Location:47276
      DUF3512; Domain of unknown function (DUF3512)
    16. XM_017315346.1XP_017170835.1  bromodomain-containing protein 9 isoform X10

      Conserved Domains (1) summary
      pfam12024
      Location:47276
      DUF3512; Domain of unknown function (DUF3512)
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