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    Tsr1 TSR1 20S rRNA accumulation [ Mus musculus (house mouse) ]

    Gene ID: 104662, updated on 12-Aug-2018

    Summary

    Official Symbol
    Tsr1provided by MGI
    Official Full Name
    TSR1 20S rRNA accumulationprovided by MGI
    Primary source
    MGI:MGI:2144566
    See related
    Ensembl:ENSMUSG00000038335 Vega:OTTMUSG00000006188
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AU040765; AW550801; mKIAA1401
    Expression
    Ubiquitous expression in placenta adult (RPKM 18.1), CNS E11.5 (RPKM 15.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tsr1 in Genome Data Viewer
    Location:
    11; 11 B5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (74898080..74909340)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (74711582..74722842)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene max binding protein Neighboring gene small G protein signaling modulator 2 Neighboring gene microRNA 6926 Neighboring gene small nucleolar RNA, C/D box 91A Neighboring gene serine racemase Neighboring gene Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) Neighboring gene ribosomal protein S12, pseudogene 19 Neighboring gene SMT3 suppressor of mif two 3 homolog 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    U3 snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    pre-rRNA-processing protein TSR1 homolog
    Names
    TSR1, 20S rRNA accumulation, homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177325.3NP_796299.2  pre-rRNA-processing protein TSR1 homolog

      See identical proteins and their annotated locations for NP_796299.2

      Status: VALIDATED

      Source sequence(s)
      AK129350, BF455129, CD547366
      Consensus CDS
      CCDS36225.1
      UniProtKB/Swiss-Prot
      Q5SWD9
      Related
      ENSMUSP00000039027.7, OTTMUSP00000006478, ENSMUST00000045807.13, OTTMUST00000013944
      Conserved Domains (5) summary
      smart00785
      Location:228309
      AARP2CN; AARP2CN (NUC121) domain
      COG5177
      Location:32774
      COG5177; Uncharacterized conserved protein [Function unknown]
      pfam04950
      Location:489772
      RIBIOP_C; 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
      cl00388
      Location:455482
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
      cl21455
      Location:140255
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      74898080..74909340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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