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    Rars arginyl-tRNA synthetase [ Mus musculus (house mouse) ]

    Gene ID: 104458, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rarsprovided by MGI
    Official Full Name
    arginyl-tRNA synthetaseprovided by MGI
    Primary source
    MGI:MGI:1914297
    See related
    Ensembl:ENSMUSG00000018848
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rars1; AL033339; AW985894; 2610011N19Rik; 2610037E21Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 41.2), CNS E11.5 (RPKM 34.3) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Rars in Genome Data Viewer
    Location:
    11; 11 A4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (35699207..35725355, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (35808381..35834528, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (35621883..35648030, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene microRNA 103-1 Neighboring gene pantothenate kinase 3 Neighboring gene fibrillarin-like 1 Neighboring gene WW, C2 and coiled-coil domain containing 1 Neighboring gene predicted gene, 42072 Neighboring gene teneurin transmembrane protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables aminoacyl-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables arginine binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables arginine-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables arginine-tRNA ligase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables arginine-tRNA ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in arginyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in arginyl-tRNA aminoacylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in arginyl-tRNA aminoacylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA aminoacylation for protein translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of aminoacyl-tRNA synthetase multienzyme complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    arginine--tRNA ligase, cytoplasmic
    Names
    argRS
    arginyl-tRNA synthetase, cytoplasmic
    NP_080212.2
    XP_036012095.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025936.3NP_080212.2  arginine--tRNA ligase, cytoplasmic

      See identical proteins and their annotated locations for NP_080212.2

      Status: VALIDATED

      Source sequence(s)
      AK076160, CB523934, CF748175
      Consensus CDS
      CCDS24544.1
      UniProtKB/Swiss-Prot
      Q9D0I9
      Related
      ENSMUSP00000018992.4, ENSMUST00000018992.4
      Conserved Domains (4) summary
      cd00671
      Location:193457
      ArgRS_core; catalytic core domain of arginyl-tRNA synthetases
      smart01016
      Location:79166
      Arg_tRNA_synt_N; Arginyl tRNA synthetase N terminal dom
      PLN02286
      Location:80660
      PLN02286; arginine-tRNA ligase
      cl12020
      Location:498660
      Anticodon_Ia_like; Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      35699207..35725355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156202.1XP_036012095.1  arginine--tRNA ligase, cytoplasmic isoform X1

      Conserved Domains (1) summary
      PLN02286
      Location:8588
      PLN02286; arginine-tRNA ligase
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