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    Cabin1 calcineurin binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 104248, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cabin1provided by MGI
    Official Full Name
    calcineurin binding protein 1provided by MGI
    Primary source
    MGI:MGI:1298375
    See related
    Ensembl:ENSMUSG00000020196
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cain; Ppp3in; A330070M20Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 14.2), ovary adult (RPKM 14.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cabin1 in Genome Data Viewer
    Location:
    10 C1; 10 38.56 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (75646110..75764361, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (75108855..75227102, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40695 Neighboring gene sushi domain containing 2 Neighboring gene predicted gene, 40696 Neighboring gene cytochrome b-c1 complex subunit 7 pseudogene Neighboring gene D-dopachrome tautomerase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 2B binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication-independent nucleosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication-independent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell death ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    aggresome ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    calcineurin-binding protein cabin-1
    Names
    calcineurin inhibitor
    protein phosphatase 3 inhibitor

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172549.3NP_766137.2  calcineurin-binding protein cabin-1

      See identical proteins and their annotated locations for NP_766137.2

      Status: VALIDATED

      Source sequence(s)
      AK039606, BC051668, BC057551, BQ714836, BU705499, CN722898, CV884170
      Consensus CDS
      CCDS35938.1
      UniProtKB/TrEMBL
      G3X8Q1, Q6PFH4, Q80X22
      Related
      ENSMUSP00000001712.6, ENSMUST00000001712.7
      Conserved Domains (4) summary
      sd00006
      Location:90118
      TPR; TPR repeat [structural motif]
      pfam09047
      Location:21232157
      MEF2_binding; MEF2 binding
      pfam13414
      Location:92155
      TPR_11; TPR repeat
      pfam13424
      Location:36120
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      75646110..75764361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513020.3XP_006513083.1  calcineurin-binding protein cabin-1 isoform X2

      Conserved Domains (4) summary
      sd00006
      Location:90118
      TPR; TPR repeat [structural motif]
      pfam09047
      Location:20942128
      MEF2_binding; MEF2 binding
      pfam13414
      Location:92155
      TPR_11; TPR repeat
      pfam13424
      Location:36120
      TPR_12; Tetratricopeptide repeat
    2. XM_006513019.3XP_006513082.1  calcineurin-binding protein cabin-1 isoform X1

      See identical proteins and their annotated locations for XP_006513082.1

      UniProtKB/TrEMBL
      G3X8Q1
      Conserved Domains (4) summary
      sd00006
      Location:90118
      TPR; TPR repeat [structural motif]
      pfam09047
      Location:21232157
      MEF2_binding; MEF2 binding
      pfam13414
      Location:92155
      TPR_11; TPR repeat
      pfam13424
      Location:36120
      TPR_12; Tetratricopeptide repeat
    3. XM_006513021.1XP_006513084.1  calcineurin-binding protein cabin-1 isoform X3

      Conserved Domains (3) summary
      sd00006
      Location:191218
      TPR; TPR repeat [structural motif]
      pfam09047
      Location:12581292
      MEF2_binding; MEF2 binding
      pfam13414
      Location:191271
      TPR_11; TPR repeat
    4. XM_006513022.1XP_006513085.1  calcineurin-binding protein cabin-1 isoform X4

      Conserved Domains (1) summary
      pfam09047
      Location:10451079
      MEF2_binding; MEF2 binding

    RNA

    1. XR_001779404.1 RNA Sequence

    2. XR_001779405.1 RNA Sequence

    3. XR_380334.3 RNA Sequence

    4. XR_001779406.1 RNA Sequence

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