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    Rhoq ras homolog family member Q [ Mus musculus (house mouse) ]

    Gene ID: 104215, updated on 8-Dec-2018

    Summary

    Official Symbol
    Rhoqprovided by MGI
    Official Full Name
    ras homolog family member Qprovided by MGI
    Primary source
    MGI:MGI:1931553
    See related
    Ensembl:ENSMUSG00000024143
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arhq; Tc10; TC10A
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 5.0), limb E14.5 (RPKM 4.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rhoq in Genome Data Viewer
    Location:
    17 E4; 17 56.9 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (86961685..87000069)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (87362451..87399409)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene transmembrane protein 247 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E2 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class F Neighboring gene cysteine-rich PDZ-binding protein Neighboring gene predicted gene, 30421

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GBD domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    profilin binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    GTP metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    PubMed 
    actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell projection assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to insulin stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cortical actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cortical actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    establishment or maintenance of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    insulin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of glucose import IC
    Inferred by Curator
    more info
    PubMed 
    negative regulation of protein localization to plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of filopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of glucose import ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell shape IDA
    Inferred from Direct Assay
    more info
    PubMed 
    small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoQ
    Names
    ras homolog gene family, member Q
    ras-like protein TC10
    ras-related GTP-binding protein TC10
    small GTPase Tc10

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145491.2NP_663466.2  rho-related GTP-binding protein RhoQ precursor

      See identical proteins and their annotated locations for NP_663466.2

      Status: PROVISIONAL

      Source sequence(s)
      BC056363
      Consensus CDS
      CCDS29010.1
      UniProtKB/Swiss-Prot
      Q8R527
      Related
      ENSMUSP00000024956.8, ENSMUST00000024956.14
      Conserved Domains (1) summary
      cd04135
      Location:10183
      Tc10; Rho GTPase TC10 (Tc10)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      86961685..87000069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001782024.1 RNA Sequence

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