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    Tbc1d10a TBC1 domain family, member 10a [ Mus musculus (house mouse) ]

    Gene ID: 103724, updated on 23-May-2018

    Summary

    Official Symbol
    Tbc1d10aprovided by MGI
    Official Full Name
    TBC1 domain family, member 10aprovided by MGI
    Primary source
    MGI:MGI:2144164
    See related
    Ensembl:ENSMUSG00000034412 Vega:OTTMUSG00000005055
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EPI64; Tbc1d10; AI447804; mFLJ00288
    Expression
    Ubiquitous expression in ovary adult (RPKM 13.5), bladder adult (RPKM 11.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tbc1d10a in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (4186833..4215507)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (4086836..4115508)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene ring finger protein 215 Neighboring gene microRNA 3060 Neighboring gene coiled-coil domain containing 157 Neighboring gene splicing factor 3a, subunit 1 Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1 Neighboring gene predicted gene 11956

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ00288

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    activation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    activation of cysteine-type endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TBC1 domain family member 10A
    Names
    EBP50-PDX interactor of 64 kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134023.1NP_598784.1  TBC1 domain family member 10A

      See identical proteins and their annotated locations for NP_598784.1

      Status: PROVISIONAL

      Source sequence(s)
      BC018300
      Consensus CDS
      CCDS56756.1
      UniProtKB/Swiss-Prot
      P58802
      Related
      ENSMUSP00000136453.1, ENSMUST00000180088.1
      Conserved Domains (1) summary
      smart00164
      Location:110313
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      4186833..4215507
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514441.2XP_006514504.1  TBC1 domain family member 10A isoform X1

      Conserved Domains (1) summary
      smart00164
      Location:22225
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
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