U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Nup107 nucleoporin 107 [ Mus musculus (house mouse) ]

    Gene ID: 103468, updated on 26-Sep-2022

    Summary

    Official Symbol
    Nup107provided by MGI
    Official Full Name
    nucleoporin 107provided by MGI
    Primary source
    MGI:MGI:2143854
    See related
    Ensembl:ENSMUSG00000052798 AllianceGenome:MGI:2143854
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nuclear pore complex assembly; nucleocytoplasmic transport; and posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane and nuclear periphery. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in embryo and neural tube. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome; nephrotic syndrome type 11; and ovarian dysgenesis 6. Orthologous to human NUP107 (nucleoporin 107). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 27.0), placenta adult (RPKM 18.7) and 22 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nup107 in Genome Data Viewer
    Location:
    10; 10 D2
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (117586526..117628641, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (117750621..117792736, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53636 Neighboring gene solute carrier family 35, member E3 Neighboring gene RAS related protein 1b Neighboring gene predicted gene, 53637 Neighboring gene predicted gene, 40773 Neighboring gene predicted gene, 32552

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in female gonad development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nephron development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear pore complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleocytoplasmic transport IC
    Inferred by Curator
    more info
    PubMed 
    involved_in post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore IC
    Inferred by Curator
    more info
    PubMed 
    part_of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore outer ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of nuclear pore outer ring ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup107
    Names
    107 kDa nucleoporin
    nucleoporin Nup107

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134010.2NP_598771.1  nuclear pore complex protein Nup107

      See identical proteins and their annotated locations for NP_598771.1

      Status: PROVISIONAL

      Source sequence(s)
      AK088069
      Consensus CDS
      CCDS36068.1
      UniProtKB/Swiss-Prot
      Q8BH74, Q99KH5
      Related
      ENSMUSP00000063590.6, ENSMUST00000064848.7
      Conserved Domains (1) summary
      pfam04121
      Location:210909
      Nup84_Nup100; Nuclear pore protein 84 / 107

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      117586526..117628641 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513018.4XP_006513081.1  nuclear pore complex protein Nup107 isoform X1

      See identical proteins and their annotated locations for XP_006513081.1

      Conserved Domains (1) summary
      pfam04121
      Location:110808
      Nup84_Nup100; Nuclear pore protein 84 / 107