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    Csnk1g2 casein kinase 1, gamma 2 [ Mus musculus (house mouse) ]

    Gene ID: 103236, updated on 5-Sep-2021

    Summary

    Official Symbol
    Csnk1g2provided by MGI
    Official Full Name
    casein kinase 1, gamma 2provided by MGI
    Primary source
    MGI:MGI:1920014
    See related
    Ensembl:ENSMUSG00000003345
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI463719; 2810429I12Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 317.9), colon adult (RPKM 106.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Csnk1g2 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80458465..80476605)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80622676..80640771)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80085525..80103516)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 4 Neighboring gene microRNA 6912 Neighboring gene predicted gene, 31298 Neighboring gene BTB (POZ) domain containing 2 Neighboring gene predicted gene, 51810 Neighboring gene MAP kinase-interacting serine/threonine kinase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    casein kinase I isoform gamma-2; casein kinase I
    Names
    CKI-gamma 2
    NP_001153063.1
    NP_598763.1
    XP_006513074.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159591.1NP_001153063.1  casein kinase I isoform gamma-2 isoform 2

      See identical proteins and their annotated locations for NP_001153063.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' UTR exon and lacks an in-frame internal segment in the CDS, as compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK132871, AK152413, CF612914
      Consensus CDS
      CCDS48638.1
      UniProtKB/Swiss-Prot
      Q8BVP5
      Related
      ENSMUSP00000082560.6, ENSMUST00000085435.7
      Conserved Domains (2) summary
      cd14126
      Location:45332
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:332374
      CK1gamma_C; Casein kinase 1 gamma C terminal
    2. NM_134002.2NP_598763.1  casein kinase I isoform gamma-2 isoform 1

      See identical proteins and their annotated locations for NP_598763.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC152410, AK077076, AK132871, AK152413, CF612914
      Consensus CDS
      CCDS24029.1
      UniProtKB/Swiss-Prot
      Q8BVP5
      UniProtKB/TrEMBL
      Q99K78
      Related
      ENSMUSP00000078706.7, ENSMUST00000079773.14
      Conserved Domains (3) summary
      COG0515
      Location:45356
      SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
      cd14126
      Location:45359
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:359401
      CK1gamma_C; Casein kinase 1 gamma C terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      80458465..80476605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513011.3XP_006513074.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_006513074.1

      UniProtKB/Swiss-Prot
      Q8BVP5
      Conserved Domains (2) summary
      cd14126
      Location:45332
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:332374
      CK1gamma_C; Casein kinase 1 gamma C terminal

    RNA

    1. XR_001779401.2 RNA Sequence

    2. XR_380333.4 RNA Sequence

    3. XR_003948572.2 RNA Sequence

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