Format

Send to:

Choose Destination
    • Showing Current items.

    Cenpi centromere protein I [ Mus musculus (house mouse) ]

    Gene ID: 102920, updated on 16-Oct-2021

    Summary

    Official Symbol
    Cenpiprovided by MGI
    Official Full Name
    centromere protein Iprovided by MGI
    Primary source
    MGI:MGI:2147897
    See related
    Ensembl:ENSMUSG00000031262
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CENP-I; Fshprh1
    Summary
    This gene encodes a protein that may be constitutively associated with centromeres and might be involved in recruiting centromere protein A to the centromere for kinetochore assembly. A similar gene in human is involved in the response of gonadal tissues to follicle-stimulating hormone. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
    Expression
    Biased expression in liver E14 (RPKM 5.1), liver E14.5 (RPKM 4.7) and 10 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cenpi in Genome Data Viewer
    Location:
    X; X E3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (133206777..133263853)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (134308084..134363104)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (130842702..130897178)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene TRM2 tRNA methyltransferase 2B Neighboring gene transmembrane protein 35A Neighboring gene dystrophin related protein 2 Neighboring gene TATA-box binding protein associated factor 7 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40943

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in centromere complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere protein I
    Names
    FSH primary response protein 1
    follicle-stimulating hormone primary response protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305631.1NP_001292560.1  centromere protein I

      See identical proteins and their annotated locations for NP_001292560.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK043344, AK085048, AK161473
      Consensus CDS
      CCDS30393.1
      UniProtKB/Swiss-Prot
      Q8K1K4
      UniProtKB/TrEMBL
      Q3TTB0
      Related
      ENSMUSP00000098809.2, ENSMUST00000101251.8
      Conserved Domains (1) summary
      pfam07778
      Location:12516
      CENP-I; Mis6
    2. NM_145924.3NP_666036.1  centromere protein I

      See identical proteins and their annotated locations for NP_666036.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK043344, AK085048, AK161473
      Consensus CDS
      CCDS30393.1
      UniProtKB/Swiss-Prot
      Q8K1K4
      UniProtKB/TrEMBL
      Q3TTB0
      Related
      ENSMUSP00000079851.6, ENSMUST00000081064.12
      Conserved Domains (1) summary
      pfam07778
      Location:12516
      CENP-I; Mis6

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      133206777..133263853
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528477.3XP_006528540.1  centromere protein I isoform X2

      Conserved Domains (1) summary
      pfam07778
      Location:12463
      CENP-I; Mis6
    2. XM_017318340.2XP_017173829.1  centromere protein I isoform X1

      UniProtKB/Swiss-Prot
      Q8K1K4
      Conserved Domains (1) summary
      pfam07778
      Location:12516
      CENP-I; Mis6
    Support Center