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    Ankrd10 ankyrin repeat domain 10 [ Mus musculus (house mouse) ]

    Gene ID: 102334, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ankrd10provided by MGI
    Official Full Name
    ankyrin repeat domain 10provided by MGI
    Primary source
    MGI:MGI:1921840
    See related
    Ensembl:ENSMUSG00000031508
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW549277; 4833425P12Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 34.9), thymus adult (RPKM 31.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ankrd10 in Genome Data Viewer
    Location:
    8; 8 A1.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (11661581..11694617, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (11611581..11635926, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (11611583..11635754, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene cysteinyl-tRNA synthetase 2 (mitochondrial)(putative) Neighboring gene inhibitor of growth family, member 1 Neighboring gene microRNA 7238 Neighboring gene RIKEN cDNA 1700016D06 gene Neighboring gene ribosomal protein S3A pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167967.2NP_001161439.1  ankyrin repeat domain-containing protein 10 isoform 2

      See identical proteins and their annotated locations for NP_001161439.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has a distinct 3' coding region and 3' UTR, compared to variant 1. These differences result in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK031808, AK039879, AK050983
      Consensus CDS
      CCDS52479.1
      UniProtKB/TrEMBL
      Q8BG46, Q8BYG1
      Related
      ENSMUSP00000131657.2, ENSMUST00000169782.3
      Conserved Domains (3) summary
      cd00204
      Location:56177
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:62154
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:5688
      ANK; ANK repeat [structural motif]
    2. NM_001281974.1NP_001268903.1  ankyrin repeat domain-containing protein 10 isoform 3

      See identical proteins and their annotated locations for NP_001268903.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK050983, AK082875, AK084456, AV319211
      UniProtKB/Swiss-Prot
      Q99LW0
      UniProtKB/TrEMBL
      Q8BG46
    3. NM_001281975.1NP_001268904.1  ankyrin repeat domain-containing protein 10 isoform 4 precursor

      See identical proteins and their annotated locations for NP_001268904.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate 5' structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at an alternate AUG and result in an isoform (4) with a shorter and distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AK050983, AK081754, AK084456, AV319211
      UniProtKB/TrEMBL
      Q8BG46
    4. NM_133971.3NP_598732.2  ankyrin repeat domain-containing protein 10 isoform 1

      See identical proteins and their annotated locations for NP_598732.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform 1.
      Source sequence(s)
      AK050983, AK082875, AK084456, AV319211
      Consensus CDS
      CCDS22098.1
      UniProtKB/Swiss-Prot
      Q99LW0
      UniProtKB/TrEMBL
      Q8BG46
      Related
      ENSMUSP00000033905.6, ENSMUST00000033905.13
      Conserved Domains (3) summary
      cd00204
      Location:56177
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:62154
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:5688
      ANK; ANK repeat [structural motif]

    RNA

    1. NR_030781.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has multiple differences compared to variant 1, including the use of an alternate promoter. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
      Source sequence(s)
      AK014768, AK039879

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      11661581..11694617 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508685.5XP_006508748.1  ankyrin repeat domain-containing protein 10 isoform X1

      Conserved Domains (2) summary
      COG0666
      Location:46188
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:5688
      ANK; ANK repeat [structural motif]
    2. XM_006508686.5XP_006508749.1  ankyrin repeat domain-containing protein 10 isoform X2

      Conserved Domains (2) summary
      sd00045
      Location:1948
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:23105
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_006508691.5XP_006508754.1  ankyrin repeat domain-containing protein 10 isoform X7

      See identical proteins and their annotated locations for XP_006508754.1

    4. XM_006508688.5XP_006508751.1  ankyrin repeat domain-containing protein 10 isoform X5

    5. XM_030243218.2XP_030099078.1  ankyrin repeat domain-containing protein 10 isoform X3

      Conserved Domains (2) summary
      sd00045
      Location:1948
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:23105
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_030243222.2XP_030099082.1  ankyrin repeat domain-containing protein 10 isoform X8

    7. XM_030243221.2XP_030099081.1  ankyrin repeat domain-containing protein 10 isoform X6

    8. XM_036153709.1XP_036009602.1  ankyrin repeat domain-containing protein 10 isoform X8

    9. XM_006508687.5XP_006508750.1  ankyrin repeat domain-containing protein 10 isoform X4

      Conserved Domains (2) summary
      COG0666
      Location:46188
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:5688
      ANK; ANK repeat [structural motif]
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