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    Gpat4 glycerol-3-phosphate acyltransferase 4 [ Mus musculus (house mouse) ]

    Gene ID: 102247, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gpat4provided by MGI
    Official Full Name
    glycerol-3-phosphate acyltransferase 4provided by MGI
    Primary source
    MGI:MGI:2142716
    See related
    Ensembl:ENSMUSG00000031545
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Agpat6; Tsarg7; AU041707; AW545732
    Expression
    Broad expression in testis adult (RPKM 56.2), CNS E11.5 (RPKM 13.2) and 24 other tissues See more
    Orthologs

    Genomic context

    See Gpat4 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (23171265..23208453, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (24283418..24318925, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene NK6 homeobox 3 Neighboring gene predicted gene, 30306 Neighboring gene predicted gene, 30247 Neighboring gene GINS complex subunit 4 (Sld5 homolog) Neighboring gene golgi autoantigen, golgin subfamily a, 7 Neighboring gene predicted gene, 39141

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    glycerol-3-phosphate O-acyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycerol-3-phosphate O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    glycerol-3-phosphate O-acyltransferase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acyl-CoA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    diacylglycerol metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glandular epithelial cell maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lactation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    mammary gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphatidylcholine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    triglyceride biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    triglyceride metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of endoplasmic reticulum membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycerol-3-phosphate acyltransferase 6
    Names
    1-AGP acyltransferase 6
    1-AGPAT 6
    1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
    LPAAT-zeta
    acyl-CoA:glycerol-3-phosphate acyltransferase 4
    lysophosphatidic acid acyltransferase zeta
    putative lysophosphatidic acid acyltransferase
    testis spermatogenesis apoptosis-related protein 7
    NP_061213.2
    XP_011240406.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018743.4NP_061213.2  glycerol-3-phosphate acyltransferase 6 precursor

      See identical proteins and their annotated locations for NP_061213.2

      Status: VALIDATED

      Source sequence(s)
      AK083589, AK169257, BY032843, BY271836
      Consensus CDS
      CCDS22189.1
      UniProtKB/Swiss-Prot
      Q8K2C8
      Related
      ENSMUSP00000127325.1, ENSMUST00000167004.2
      Conserved Domains (1) summary
      cd07991
      Location:218427
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      23171265..23208453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242104.2XP_011240406.1  glycerol-3-phosphate acyltransferase 6 isoform X1

      See identical proteins and their annotated locations for XP_011240406.1

      Conserved Domains (1) summary
      cd07991
      Location:218433
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
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