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    Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 102060, updated on 23-Nov-2023


    Official Symbol
    Gadd45gip1provided by MGI
    Official Full Name
    growth arrest and DNA-damage-inducible, gamma interacting protein 1provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000033751 AllianceGenome:MGI:1914947
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Crif1; Plinp1; MRP-L59; 2310040G17Rik
    Enables mitochondrial ribosome binding activity. Acts upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; intestine epithelium; and secondary oocyte. Used to study type 2 diabetes mellitus. Orthologous to human GADD45GIP1 (GADD45G interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in adrenal adult (RPKM 129.2), ovary adult (RPKM 87.8) and 28 other tissues See more
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    Genomic context

    See Gadd45gip1 in Genome Data Viewer
    8 C3; 8 41.19 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2023_04 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (85558911..85562111)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (84832282..84835482)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA G430095P16 gene Neighboring gene nuclear factor I/X Neighboring gene VISTA enhancer mm21 Neighboring gene VISTA enhancer mm1615 Neighboring gene DAN domain family member 5, BMP antagonist Neighboring gene RIKEN cDNA 1700122E12 gene Neighboring gene RAD23 homolog A, nucleotide excision repair protein Neighboring gene calreticulin Neighboring gene predicted gene 5911

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding IDA
    Inferred from Direct Assay
    more info
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info

    General protein information

    Preferred Names
    large ribosomal subunit protein mL64
    39S ribosomal protein L59, mitochondrial
    growth arrest and DNA damage-inducible proteins-interacting protein 1
    papillomavirus L2 interacting nuclear protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183358.4NP_899202.3  large ribosomal subunit protein mL64

      See identical proteins and their annotated locations for NP_899202.3

      Status: VALIDATED

      Source sequence(s)
      AK002738, AK028227
      Consensus CDS
      Q8BT05, Q9CR59
      ENSMUSP00000037783.6, ENSMUST00000036734.6
      Conserved Domains (1) summary
      CR6_interact; Growth arrest and DNA-damage-inducible proteins-interacting protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000074.7 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)