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    Ints4 integrator complex subunit 4 [ Mus musculus (house mouse) ]

    Gene ID: 101861, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ints4provided by MGI
    Official Full Name
    integrator complex subunit 4provided by MGI
    Primary source
    MGI:MGI:1917164
    See related
    Ensembl:ENSMUSG00000025133
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA692684; AW493223; 2610034N24Rik
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 15.6), ovary adult (RPKM 14.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ints4 in Genome Data Viewer
    Location:
    7; 7 E1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (97480951..97541398)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (104629466..104689908)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32945 Neighboring gene potassium channel tetramerisation domain containing 14 Neighboring gene adipogenesis associated Mth938 domain containing Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, pseudogene 1 Neighboring gene remodeling and spacing factor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    snRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    snRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integrator complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integrator complex subunit 4
    Names
    int4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358012.1NP_001344941.1  integrator complex subunit 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC149605
      Conserved Domains (2) summary
      sd00044
      Location:367394
      HEAT; HEAT repeat [structural motif]
      cl26317
      Location:371452
      Adaptin_N; Adaptin N terminal region
    2. NM_027256.2NP_081532.1  integrator complex subunit 4 isoform 1

      See identical proteins and their annotated locations for NP_081532.1

      Status: VALIDATED

      Source sequence(s)
      AC149605, AK011676, AW493223, CA450656, CF724981, CX218921, CX565861
      Consensus CDS
      CCDS21460.1
      UniProtKB/Swiss-Prot
      Q8CIM8
      Related
      ENSMUSP00000026126.8, ENSMUST00000026126.9
      Conserved Domains (2) summary
      COG1413
      Location:52257
      HEAT; HEAT repeat [General function prediction only]
      sd00044
      Location:200222
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      97480951..97541398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507180.1XP_006507243.1  integrator complex subunit 4 isoform X2

      Conserved Domains (2) summary
      sd00044
      Location:367394
      HEAT; HEAT repeat [structural motif]
      cl26317
      Location:371452
      Adaptin_N; Adaptin N terminal region
    2. XM_006507179.3XP_006507242.1  integrator complex subunit 4 isoform X1

      See identical proteins and their annotated locations for XP_006507242.1

      Conserved Domains (2) summary
      COG1413
      Location:51256
      HEAT; HEAT repeat [General function prediction only]
      sd00044
      Location:199221
      HEAT; HEAT repeat [structural motif]
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