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    Tmem168 transmembrane protein 168 [ Mus musculus (house mouse) ]

    Gene ID: 101118, updated on 18-Sep-2024

    Summary

    Official Symbol
    Tmem168provided by MGI
    Official Full Name
    transmembrane protein 168provided by MGI
    Primary source
    MGI:MGI:1921794
    See related
    Ensembl:ENSMUSG00000029569 AllianceGenome:MGI:1921794
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5730526F17Rik; 8430437G11Rik
    Summary
    Predicted to be located in transport vesicle. Is expressed in cerebral cortex ventricular layer and heart ventricle. Orthologous to human TMEM168 (transmembrane protein 168). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 7.0), bladder adult (RPKM 6.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmem168 in Genome Data Viewer
    Location:
    6 A1; 6 5.68 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (13580688..13608097, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (13580689..13608098, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S10 pseudogene Neighboring gene STARR-seq mESC enhancer starr_15194 Neighboring gene predicted gene, 25737 Neighboring gene STARR-seq mESC enhancer starr_15196 Neighboring gene STARR-positive B cell enhancer ABC_E10370 Neighboring gene STARR-seq mESC enhancer starr_15197 Neighboring gene base methyltransferase of 25S rRNA 2 Neighboring gene STARR-positive B cell enhancer ABC_E2186 Neighboring gene predicted gene, 53312

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1)  1 citation
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables sodium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sodium channel regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in transport vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028990.5NP_083266.1  transmembrane protein 168

      See identical proteins and their annotated locations for NP_083266.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer, protein-coding transcript.
      Source sequence(s)
      AC139884, AK051532
      Consensus CDS
      CCDS19915.1
      UniProtKB/Swiss-Prot
      Q3TDA5, Q91VX9
      Related
      ENSMUSP00000031554.3, ENSMUST00000031554.9

    RNA

    1. NR_155435.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AC139884
      Related
      ENSMUST00000149123.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      13580688..13608097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504953.5XP_006505016.1  transmembrane protein 168 isoform X1

      See identical proteins and their annotated locations for XP_006505016.1

      UniProtKB/Swiss-Prot
      Q3TDA5, Q91VX9
    2. XM_006504952.5XP_006505015.1  transmembrane protein 168 isoform X1

      See identical proteins and their annotated locations for XP_006505015.1

      UniProtKB/Swiss-Prot
      Q3TDA5, Q91VX9

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001347059.1: Suppressed sequence

      Description
      NM_001347059.1: This RefSeq was removed because currently there is support for the transcript but not for the protein.