Format

Send to:

Choose Destination
    • Showing Current items.

    Pds5b PDS5 cohesin associated factor B [ Mus musculus (house mouse) ]

    Gene ID: 100710, updated on 19-Mar-2019

    Summary

    Official Symbol
    Pds5bprovided by MGI
    Official Full Name
    PDS5 cohesin associated factor Bprovided by MGI
    Primary source
    MGI:MGI:2140945
    See related
    Ensembl:ENSMUSG00000034021
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AS3; Aprin; AI646570; AW212954; WAP-Her-2; mKIAA0979; Tg(Wap-ERBB2)229Wzw
    Expression
    Broad expression in CNS E11.5 (RPKM 11.8), limb E14.5 (RPKM 9.2) and 22 other tissues See more
    Orthologs

    Genomic context

    See Pds5b in Genome Data Viewer
    Location:
    5; 5 G3
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (150673744..150810669)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (151476402..151613244)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene NEDD4 binding protein 2-like 1 Neighboring gene NEDD4 binding protein 2-like 2 Neighboring gene predicted gene, 40353 Neighboring gene predicted gene, 36447 Neighboring gene klotho

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    lens development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    neuroblast migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sister chromatid cohesion protein PDS5 homolog B
    Names
    Her-2 Tg
    PDS5, regulator of cohesion maintenance, homolog B
    androgen-induced proliferation inhibitor
    androgen-induced prostate proliferative shutoff associated protein AS3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346503.1NP_001333432.1  sister chromatid cohesion protein PDS5 homolog B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC111126, AC158558
      Consensus CDS
      CCDS85012.1
      UniProtKB/Swiss-Prot
      Q4VA53
    2. NM_175310.6NP_780519.3  sister chromatid cohesion protein PDS5 homolog B isoform 1

      See identical proteins and their annotated locations for NP_780519.3

      Status: VALIDATED

      Source sequence(s)
      AK047172, BC096539, BF471938, BY243250, CX210004
      Consensus CDS
      CCDS39412.1
      UniProtKB/Swiss-Prot
      Q4VA53
      Related
      ENSMUSP00000016569.4, ENSMUST00000016569.10
      Conserved Domains (2) summary
      sd00044
      Location:240261
      HEAT; HEAT repeat [structural motif]
      cl04813
      Location:11721275
      EIN3; Ethylene insensitive 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      150673744..150810669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504901.1XP_006504964.1  sister chromatid cohesion protein PDS5 homolog B isoform X1

      UniProtKB/TrEMBL
      F8WHU5
      Related
      ENSMUSP00000038421.8, ENSMUST00000038900.14
      Conserved Domains (2) summary
      pfam16001
      Location:11681426
      DUF4775; Domain of unknown function (DUF4775)
      sd00044
      Location:240261
      HEAT; HEAT repeat [structural motif]
    2. XM_006504903.1XP_006504966.1  sister chromatid cohesion protein PDS5 homolog B isoform X3

      Conserved Domains (2) summary
      sd00044
      Location:240261
      HEAT; HEAT repeat [structural motif]
      cl04813
      Location:11721275
      EIN3; Ethylene insensitive 3
    3. XM_006504904.1XP_006504967.1  sister chromatid cohesion protein PDS5 homolog B isoform X4

      Conserved Domains (2) summary
      pfam16001
      Location:11471405
      DUF4775; Domain of unknown function (DUF4775)
      sd00044
      Location:240261
      HEAT; HEAT repeat [structural motif]
    4. XM_006504902.2XP_006504965.1  sister chromatid cohesion protein PDS5 homolog B isoform X2

      Related
      ENSMUSP00000144572.1, ENSMUST00000202170.3
      Conserved Domains (2) summary
      pfam16001
      Location:11681425
      DUF4775; Domain of unknown function (DUF4775)
      sd00044
      Location:240261
      HEAT; HEAT repeat [structural motif]
    5. XM_006504905.2XP_006504968.1  sister chromatid cohesion protein PDS5 homolog B isoform X5

      Conserved Domains (2) summary
      pfam16001
      Location:9271194
      DUF4775; Domain of unknown function (DUF4775)
      sd00044
      Location:3262
      HEAT; HEAT repeat [structural motif]
    Support Center