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    Il4i1b interleukin 4 induced 1B [ Mus musculus (house mouse) ]

    Gene ID: 100328588, updated on 23-Jun-2021

    Summary

    Official Symbol
    Il4i1bprovided by MGI
    Official Full Name
    interleukin 4 induced 1Bprovided by MGI
    Primary source
    MGI:MGI:5439399
    See related
    Ensembl:ENSMUSG00000074141
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LAO; Fig1; LAAO; Il4i1; mFIG1; Gm21948; Nup62-il4i1
    Summary
    This locus represents naturally-occurring readthrough transcription between Nup62 (nucleoporin 62) and Il4i1 (interleukin 4 induced 1). It encodes a protein sharing similarity with the protein encoded by Il4i1, but with a longer and distinct N-terminus. [provided by RefSeq, Aug 2015]
    Expression
    Biased expression in spleen adult (RPKM 63.6), testis adult (RPKM 40.1) and 14 other tissues See more
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    Genomic context

    See Il4i1b in Genome Data Viewer
    Location:
    7 B3; 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44465794..44490228)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (44816370..44840804)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (52071740..52096174)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vaccinia related kinase 3 Neighboring gene predicted gene, 29791 Neighboring gene activating transcription factor 5 Neighboring gene nucleoporin 62 Neighboring gene interleukin 4 induced 1 Neighboring gene TBC1 domain family, member 17 Neighboring gene AKT1 substrate 1 (proline-rich) Neighboring gene microRNA 707 Neighboring gene polynucleotide kinase 3'- phosphatase Neighboring gene prostate tumor over expressed gene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    General gene information

    Markers

    Readthrough Il4i1b

    Included genes: Il4i1, Nup62

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-amino-acid oxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in immunological synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm midpiece ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    L-amino-acid oxidase
    Names
    IL4-induced protein 1
    Interleukin-4-induced protein 1
    Protein Fig-1
    NP_001164495.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001171024.1NP_001164495.1  L-amino-acid oxidase precursor

      Status: VALIDATED

      Source sequence(s)
      AK133082, BG276482, BY087056
      Consensus CDS
      CCDS52236.1
      UniProtKB/Swiss-Prot
      O09046
      UniProtKB/TrEMBL
      D3Z4E0
      Related
      ENSMUSP00000113726.2, ENSMUST00000118125.9
      Conserved Domains (1) summary
      pfam01593
      Location:83511
      Amino_oxidase; Flavin containing amine oxidoreductase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      44465794..44490228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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