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    Gpn2 GPN-loop GTPase 2 [ Mus musculus (house mouse) ]

    Gene ID: 100210, updated on 23-May-2018

    Summary

    Official Symbol
    Gpn2provided by MGI
    Official Full Name
    GPN-loop GTPase 2provided by MGI
    Primary source
    MGI:MGI:2140368
    See related
    Ensembl:ENSMUSG00000028848 Vega:OTTMUSG00000011156
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R74630; Atpbd1b; AI838661
    Expression
    Ubiquitous expression in ovary adult (RPKM 24.7), duodenum adult (RPKM 20.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gpn2 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (133584373..133591735)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (133140288..133147650)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 0, group B, member 2 Neighboring gene G patch domain containing 3 Neighboring gene predicted gene, 42324 Neighboring gene stratifin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GPN-loop GTPase 2
    Names
    ATP binding domain 1 family, member B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290742.1NP_001277671.1  GPN-loop GTPase 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AL627228
      Consensus CDS
      CCDS71484.1
      UniProtKB/TrEMBL
      A2A9F7
      Related
      ENSMUSP00000101519.1, OTTMUSP00000011963, ENSMUST00000105899.1, OTTMUST00000026138
      Conserved Domains (2) summary
      COG1100
      Location:13159
      Gem1; GTPase SAR1 family domain [General function prediction only]
      pfam03029
      Location:14238
      ATP_bind_1; Conserved hypothetical ATP binding protein
    2. NM_133884.2NP_598645.2  GPN-loop GTPase 2 isoform 1

      See identical proteins and their annotated locations for NP_598645.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BQ552936, CN721622, CO798620
      Consensus CDS
      CCDS18753.1
      UniProtKB/Swiss-Prot
      Q8VEJ1
      Related
      ENSMUSP00000030661.7, OTTMUSP00000011962, ENSMUST00000030661.13, OTTMUST00000026137
      Conserved Domains (2) summary
      COG1100
      Location:13182
      Gem1; GTPase SAR1 family domain [General function prediction only]
      pfam03029
      Location:14261
      ATP_bind_1; Conserved hypothetical ATP binding protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      133584373..133591735
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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