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    NPIPB5 nuclear pore complex interacting protein family member B5 [ Homo sapiens (human) ]

    Gene ID: 100132247, updated on 8-Nov-2023

    Summary

    Official Symbol
    NPIPB5provided by HGNC
    Official Full Name
    nuclear pore complex interacting protein family member B5provided by HGNC
    Primary source
    HGNC:HGNC:37233
    See related
    Ensembl:ENSG00000243716 AllianceGenome:HGNC:37233
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in skin (RPKM 35.9), bone marrow (RPKM 26.2) and 24 other tissues See more
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    Genomic context

    See NPIPB5 in Genome Data Viewer
    Location:
    16p12.2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (22503599..22536535)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (22781607..22814310)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (22514920..22547856)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene RRN3 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7270 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:22458379-22458880 Neighboring gene SMG1 pseudogene 1 Neighboring gene small nucleolar RNA U13 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:22510885-22511742 Neighboring gene uncharacterized LOC105371131 Neighboring gene OTOA pseudogene 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:22585646-22585849 Neighboring gene uncharacterized LOC112268175 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:22593503-22594003

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ61599, MGC70907, DKFZp564D113

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex-interacting protein family member B5
    Names
    nuclear pore complex interacting protein related

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135865.3NP_001129337.1  nuclear pore complex-interacting protein family member B5

      See identical proteins and their annotated locations for NP_001129337.1

      Status: VALIDATED

      Source sequence(s)
      AC106788
      Consensus CDS
      CCDS45443.1
      UniProtKB/Swiss-Prot
      A8MRT5, B4DK13
      Conserved Domains (3) summary
      PHA03307
      Location:8711131
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam06409
      Location:46303
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:241
      AFD_class_I; Adenylate forming domain, Class I superfamily
    2. NM_001395849.1NP_001382778.1  nuclear pore complex-interacting protein family member B5

      Status: VALIDATED

      Source sequence(s)
      AC106788
      Consensus CDS
      CCDS45443.1
      UniProtKB/Swiss-Prot
      A8MRT5, B4DK13
      Related
      ENSP00000440703.1, ENST00000424340.7
      Conserved Domains (3) summary
      PHA03307
      Location:8711131
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam06409
      Location:46303
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:241
      AFD_class_I; Adenylate forming domain, Class I superfamily
    3. NM_001395850.1NP_001382779.1  nuclear pore complex-interacting protein family member B5

      Status: VALIDATED

      Source sequence(s)
      AC106788
      Consensus CDS
      CCDS45443.1
      UniProtKB/Swiss-Prot
      A8MRT5, B4DK13
      Related
      ENSP00000430633.1, ENST00000517539.5
      Conserved Domains (3) summary
      PHA03307
      Location:8711131
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam06409
      Location:46303
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:241
      AFD_class_I; Adenylate forming domain, Class I superfamily
    4. NM_001395851.1NP_001382780.1  nuclear pore complex-interacting protein family member B5

      Status: VALIDATED

      Source sequence(s)
      AC106788
      Consensus CDS
      CCDS45443.1
      UniProtKB/Swiss-Prot
      A8MRT5, B4DK13
      Conserved Domains (3) summary
      PHA03307
      Location:8711131
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam06409
      Location:46303
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:241
      AFD_class_I; Adenylate forming domain, Class I superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      22503599..22536535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_017852933.1 Reference GRCh38.p14 PATCHES

      Range
      568502..601442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      22781607..22814310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)