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    Srp54c signal recognition particle 54C [ Mus musculus (house mouse) ]

    Gene ID: 100101806, updated on 23-Jun-2021

    Summary

    Official Symbol
    Srp54cprovided by MGI
    Official Full Name
    signal recognition particle 54Cprovided by MGI
    Primary source
    MGI:MGI:3714359
    See related
    Ensembl:ENSMUSG00000079108
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E330029E12Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 30.5), bladder adult (RPKM 26.6) and 28 other tissues See more
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    Genomic context

    See Srp54c in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (55276896..55326120)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (55230118..55279331)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (56331465..56364007)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene signal recognition particle 54B Neighboring gene family with sequence similarity 177 member A2 Neighboring gene predicted gene 2446 Neighboring gene protein phosphatase 2, regulatory subunit B'', gamma Neighboring gene protein only RNase P catalytic subunit Neighboring gene ribosomal protein L18A, pseudogene 1 Neighboring gene proteasome subunit alpha 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC6231

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 7S RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables 7S RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables endoplasmic reticulum signal peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables endoplasmic reticulum signal peptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane, translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in granulocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to ER ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of signal recognition particle, endoplasmic reticulum targeting ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    signal recognition particle 54C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100110.2NP_001093580.1  signal recognition particle 54C isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC174776
      Consensus CDS
      CCDS49067.1
      UniProtKB/TrEMBL
      E9PXC0
      Related
      ENSMUSP00000151681.2, ENSMUST00000218879.2
      Conserved Domains (1) summary
      TIGR01425
      Location:2430
      SRP54_euk; signal recognition particle protein SRP54
    2. NM_001377038.1NP_001363967.1  signal recognition particle 54C isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC166323, AC174776
      Conserved Domains (1) summary
      TIGR01425
      Location:2430
      SRP54_euk; signal recognition particle protein SRP54

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      55276896..55326120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157136.1XP_036013029.1  signal recognition particle 54C isoform X2

      Conserved Domains (2) summary
      TIGR01425
      Location:2430
      SRP54_euk; signal recognition particle protein SRP54
      pfam14774
      Location:468500
      FAM177; FAM177 family
    2. XM_011243971.4XP_011242273.1  signal recognition particle 54C isoform X1

      Conserved Domains (1) summary
      TIGR01425
      Location:4291
      SRP54_euk; signal recognition particle protein SRP54
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