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    cdc42ep4b CDC42 effector protein (Rho GTPase binding) 4b [ Danio rerio (zebrafish) ]

    Gene ID: 100002938, updated on 14-Feb-2019

    Summary

    Official Symbol
    cdc42ep4bprovided by ZNC
    Official Full Name
    CDC42 effector protein (Rho GTPase binding) 4bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091008-2
    See related
    Ensembl:ENSDARG00000045036
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Orthologs

    Genomic context

    See cdc42ep4b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (37408816..37449470, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (37234316..37274701, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 12 NC_007123.5 (38946661..38987300, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene si:ch211-152f22.4 Neighboring gene tektin 3 Neighboring gene sidekick cell adhesion molecule 2b Neighboring gene uncharacterized LOC101884792

    Genomic regions, transcripts, and products

    General gene information

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    GTP-Rho binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of pseudopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      37408816..37449470 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003199641.5XP_003199689.1  cdc42 effector protein 4

      UniProtKB/TrEMBL
      E7F7G6
      Related
      ENSDARP00000127185.1, ENSDART00000152951.2
      Conserved Domains (2) summary
      pfam14957
      Location:108217
      BORG_CEP; Cdc42 effector
      cl00113
      Location:2653
      CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
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