| Data indicate that histone demethylases KDM4A/C regulate H3K9 and H3K36 methylation on brain-derived neurotrophic factor (BDNF) versus astroglial glial fibrillary acidic protein (GFAP) genes in neural stem cells. | Gene-specific methylation control of H3K9 and H3K36 on neurotrophic BDNF versus astroglial GFAP genes by KDM4A/C regulates neural stem cell differentiation.
Cascante A, Klum S, Biswas M, Antolin-Fontes B, Barnabé-Heider F, Hermanson O. | 12/20/2014 |
| Progesterone promotes neuroprotection following traumatic brain injury by inhibiting the expression of Nogo-A and GFAP, and increasing GAP-43 expression. | Progesterone alters Nogo-A, GFAP and GAP-43 expression in a rat model of traumatic brain injury.
Liu F, Liao F, Li W, Han Y, Liao D. | 10/25/2014 |
| GFAP expression study also showed that cortical layer I usually contained multiple large astrocytes with branching processes, as well as numerous smaller processes with high intensity of expression. | [Neuronal and glial antigen distribution in the columns of somatosensory cortex of rat brain (an immunohistochemical study)].
Kirichenko EIu, Logvinov AK, Povilaĭtite PE, Grankina AO. | 10/18/2014 |
| GFAP repression is mediated through direct binding of p-PPARgamma (S112) to its promoter region. | CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes.
Rai A, Tripathi S, Kushwaha R, Singh P, Srivastava P, Sanyal S, Bandyopadhyay S., Free PMC Article | 09/6/2014 |
| GFAP is an important marker in determining the severity of traumatic brain injury. | Investigation of the course of GFAP in blood in the initial 24 hours in rats subjected to minor head trauma.
Cikriklar HI, Ekici MA, Ozbek Z, Cosan DT, Baydemir C, Yürümez Y. | 03/29/2014 |
| To clarify whether GFAP-positive neoplastic astrocytes exist in rat spontaneous oligodendrogliomas and mixed gliomas or not, immunohistochemical examination was performed on spontaneous oligodendrogliomas (26 cases) and mixed gliomas. | GFAP-positive neoplastic astrocytes in spontaneous oligodendrogliomas and mixed gliomas of rats.
Nagatani M, Yamakawa S, Saito T, Ando R, Hoshiya T, Tamura K, Uchida K. | 11/2/2013 |
| Findings indicate the reciprocal relationships between GFAP expression and astrocyte neurotrophic activity by linking the ERalpha to ERbeta ratio to GFAP expression. | Age increase of estrogen receptor-α (ERα) in cortical astrocytes impairs neurotrophic support in male and female rats.
Arimoto JM, Wong A, Rozovsky I, Lin SW, Morgan TE, Finch CE., Free PMC Article | 07/27/2013 |
| TMJ inflammation induced significant upregulation of GFAP (an astroglial marker) in the trigeminal subnucleus caudalis. | A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation.
Wang S, Song L, Tan Y, Ma Y, Tian Y, Jin X, Lim G, Zhang S, Chen L, Mao J., Free PMC Article | 06/1/2013 |
| Western blot analysis showed that the chronic stress downregulated GFAP but upregulated NDRG2 protein | Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus.
Araya-Callís C, Hiemke C, Abumaria N, Flugge G., Free PMC Article | 03/9/2013 |
| In the hippocampus, thalamus, and piriform cortex both vascular laminin and astrocytic GFAP expression are upregulated following kainic acid injection. | Temporal progression of kainic acid induced changes in vascular laminin expression in rat brain with neuronal and glial correlates.
Sarkar S, Raymick J, Schmued L. | 09/15/2012 |
| Increases in c-fos and GFAP were triggered by the combined stress of non-thermal irradiation and the toxic effect of picrotoxin on cerebral tissues. | A study of neurotoxic biomarkers, c-fos and GFAP after acute exposure to GSM radiation at 900 MHz in the picrotoxin model of rat brains.
Carballo-Quintás M, Martínez-Silva I, Cadarso-Suárez C, Alvarez-Figueiras M, Ares-Pena FJ, López-Martín E. | 04/28/2012 |
| There was a reduction in GFAP levels in the hippocampus of non-trained diabetic animals, which was not found in trained diabetic group. | Effects of physical exercise on spatial memory and astroglial alterations in the hippocampus of diabetic rats.
de Senna PN, Ilha J, Baptista PP, do Nascimento PS, Leite MC, Paim MF, Gonçalves CA, Achaval M, Xavier LL. | 04/14/2012 |
| Zuogui Pill may have protective effects on the optic nerve and retina ganglion cells after contusion by promoting nestin and GFAP expressions in Muller cells of the retina. | [Protective effects of Chinese herbal medicine Zuogui Pill on retina ganglion cells after optical nerve clipping injury in rats].
Wang YQ, Li XF, Zhou X, Liu XQ, Wang WP. | 03/17/2012 |
| Activation of a pro-survival IL-6/JAK2/STAT3 cascade contributes to cholera toxin-induced GFAP expression. | Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells.
Shu M, Zhou Y, Zhu W, Wu S, Zheng X, Yan G., Free PMC Article | 12/10/2011 |
| Cesarean section might increase GFAP expression in the hippocampus and frontal cortex, and trigger neuronal apoptosis of hippocampus region. | [Alterations of glial fibrillary acidic protein expression and neural apoptosis in brain of rat offspring born by cesarean section].
Hu ZY, Huang JY, Fang MR, Wang J, Li Y, Wu LZ, Liu L, Chen L, Han S. | 12/3/2011 |
| GFAP-positive temporomandibular joint disc cells were characterized by broader processes and existed exclusively in the deeper area. | Phenotypes of articular disc cells in the rat temporomandibular joint as demonstrated by immunohistochemistry for nestin and GFAP.
Miyako H, Suzuki A, Nozawa-Inoue K, Magara J, Kawano Y, Ono K, Maeda T., Free PMC Article | 11/26/2011 |
| GFAP expression was down-regulated while GAP-43 expression upregulated in the retinal ganglial cells after peripheral nerve transplantation. | [Changes in glial fibrillary acidic protein and growth-associated protein-43 expressions in retinal ganglial cells during axonal regeneration].
Zeng Y, Wan J, Wan K, Li YY, Li LY, Wang TH, Feng ZT, Jin SX, Li Y. | 09/24/2011 |
| Region-specific alterations in the gene expression of GFAP, VEGF, and FGF-2 and their receptors in the aged brain correspond to changes in astrocytic reactivity, supporting astrocytic heterogeneity and demonstrating a differential aging effect. | Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells.
Bernal GM, Peterson DA., Free PMC Article | 09/17/2011 |
| GFAP content was diminished after a long-term administration of progesterone in hippocampus. | Short- and long-term treatment with estradiol or progesterone modifies the expression of GFAP, MAP2 and Tau in prefrontal cortex and hippocampus.
Camacho-Arroyo I, González-Arenas A, Espinosa-Raya J, Piña-Medina AG, Picazo O. | 09/3/2011 |
| There is a differential expression pattern of GFAP in the rat brain during pregnancy and the beginning of lactation that is associated with changes in brain function during these reproductive stages. | Changes in the content of GFAP in the rat brain during pregnancy and the beginning of lactation.
Gómora-Arrati P, González-Arenas A, Balandrán-Ruiz MA, Mendoza-Magaña ML, González-Flores O, Camacho-Arroyo I. | 08/6/2011 |
| Data show that astrocyte structural proteins GFAP and vimentin are induced by chronic leptin administration, suggesting astrocytes participating in leptin modulated synaptic inputs. | Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels.
García-Cáceres C, Fuente-Martín E, Burgos-Ramos E, Granado M, Frago LM, Barrios V, Horvath T, Argente J, Chowen JA., Free PMC Article | 07/23/2011 |
| Butylphthalide may protect the neuron-vascular unit of the hippocampus of Alzheimer model rats by inhibiting the expression of GFAP and increasing the expression of VEGF. | [Effect of butylphthalide on the expression of GFAP and VEGF in the hippocampus of rats with Alzheimer's disease].
Hou D, Xue L, Chen K, Tian Y, Wan S. | 06/4/2011 |
| Pax3 negatively regulates GFAP expression during astrocyte differentiation in vitro | Downregulation of Pax3 expression correlates with acquired GFAP expression during NSC differentiation towards astrocytes.
Liu Y, Zhu H, Liu M, Du J, Qian Y, Wang Y, Ding F, Gu X. | 05/28/2011 |
| these results indicate that intracellular cAMP levels regulate the expression of NPP1 in rat C6 glioma cells by a signalling pathway that is different from the GFAP signal transduction pathway | Cyclic AMP-dependent down regulation of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) in rat C6 glioma.
Aerts I, Grobben B, Van Ostade X, Slegers H. | 04/30/2011 |
| hyperbaric oxygenation treatment for cerebral infarction, can increase the expression of Map-2 and decrease the expression of GFAP. | [Influence of hyperbaric oxygen treatment on neural plasticity in experimental rats].
Ma MM, Zhang L, Liu BQ. | 04/2/2011 |