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DMTF1 cyclin D binding myb like transcription factor 1 [ Homo sapiens (human) ]

Gene ID: 9988, updated on 27-Feb-2020

Summary

Official Symbol
DMTF1provided by HGNC
Official Full Name
cyclin D binding myb like transcription factor 1provided by HGNC
Primary source
HGNC:HGNC:14603
See related
Ensembl:ENSG00000135164 MIM:608491
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DMP1; DMTF; MRUL; hDMP1
Summary
This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Expression
Ubiquitous expression in testis (RPKM 18.8), lymph node (RPKM 11.3) and 25 other tissues See more
Orthologs

Genomic context

See DMTF1 in Genome Data Viewer
Location:
7q21.12
Exon count:
24
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (87152361..87196332)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (86781677..86825648)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 3 Neighboring gene uncharacterized LOC107986814 Neighboring gene KIAA1324 like Neighboring gene uncharacterized LOC112268008 Neighboring gene uncharacterized LOC101927420 Neighboring gene uncharacterized LOC105375384 Neighboring gene transmembrane protein 243 Neighboring gene TP53 target 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.
NHGRI GWA Catalog
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25188, FLJ41265, FLJ76054

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
cyclin-D-binding Myb-like transcription factor 1
Names
cyclin D-binding Myb-like protein
cyclin-D-interacting Myb-like protein 1
hDMTF1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029536.1 RefSeqGene

    Range
    5001..48972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001142326.1NP_001135798.1  cyclin-D-binding Myb-like transcription factor 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks a 5' coding exon, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (b) with a shorter N-terminus compared to isoform a.
    Source sequence(s)
    AC005076, AF052102, AK002073, AK296211, BC070064
    Consensus CDS
    CCDS47633.1
    UniProtKB/Swiss-Prot
    Q9Y222
    UniProtKB/TrEMBL
    B3KMJ8
    Related
    ENSP00000412532.2, ENST00000432937.6
    Conserved Domains (4) summary
    smart00717
    Location:186242
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:250300
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:186241
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:140196
    Myb_DNA-bind_6; Myb-like DNA-binding domain
  2. NM_001142327.1NP_001135799.1  cyclin-D-binding Myb-like transcription factor 1 isoform a

    See identical proteins and their annotated locations for NP_001135799.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AC005076, AF084530, AK002073, BC007418, DB069894
    Consensus CDS
    CCDS5601.1
    UniProtKB/Swiss-Prot
    Q9Y222
    UniProtKB/TrEMBL
    B3KMJ8
    Related
    ENSP00000332171.7
    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  3. NM_021145.3NP_066968.3  cyclin-D-binding Myb-like transcription factor 1 isoform a

    See identical proteins and their annotated locations for NP_066968.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a, also known as DMP1alpha). Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AK002073, BC007447, BC070064, DB061156
    Consensus CDS
    CCDS5601.1
    UniProtKB/Swiss-Prot
    Q9Y222
    UniProtKB/TrEMBL
    B3KMJ8
    Related
    ENSP00000378193.5, ENST00000394703.9
    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

RNA

  1. NR_024549.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two alternate internal exons and uses an alternate splice site, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as in variant 1, would result in nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC005076, AF202145, AK002073, BC007418, DB069894
    Related
    ENST00000447863.5
  2. NR_024550.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks two alternate internal exons and uses an alternate splice site, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as in variant 1, would result in nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC005076, AF202144, AK002073, BC007418, DB069894
    Related
    ENST00000579677.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    87152361..87196332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447020.1XP_024302788.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  2. XM_024447018.1XP_024302786.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  3. XM_011516739.3XP_011515041.1  cyclin-D-binding Myb-like transcription factor 1 isoform X2

    See identical proteins and their annotated locations for XP_011515041.1

    Conserved Domains (4) summary
    smart00717
    Location:233289
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:297347
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:233288
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:187243
    Myb_DNA-bind_6; Myb-like DNA-binding domain
  4. XM_017012870.2XP_016868359.1  cyclin-D-binding Myb-like transcription factor 1 isoform X5

  5. XM_017012877.1XP_016868366.1  cyclin-D-binding Myb-like transcription factor 1 isoform X7

    Conserved Domains (2) summary
    smart00717
    Location:70123
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  6. XM_017012876.1XP_016868365.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  7. XM_017012874.1XP_016868363.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  8. XM_011516737.1XP_011515039.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    See identical proteins and their annotated locations for XP_011515039.1

    UniProtKB/Swiss-Prot
    Q9Y222
    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  9. XM_017012868.1XP_016868357.1  cyclin-D-binding Myb-like transcription factor 1 isoform X3

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:105438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  10. XM_024447024.1XP_024302792.1  cyclin-D-binding Myb-like transcription factor 1 isoform X4

    Conserved Domains (3) summary
    pfam00249
    Location:215270
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:169225
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:13379
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  11. XM_024447022.1XP_024302790.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  12. XM_024447016.1XP_024302784.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  13. XM_017012869.1XP_016868358.1  cyclin-D-binding Myb-like transcription factor 1 isoform X4

    Conserved Domains (3) summary
    pfam00249
    Location:215270
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:169225
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:13379
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  14. XM_024447026.1XP_024302794.1  cyclin-D-binding Myb-like transcription factor 1 isoform X7

    Conserved Domains (2) summary
    smart00717
    Location:70123
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  15. XM_024447017.1XP_024302785.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  16. XM_024447021.1XP_024302789.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  17. XM_024447019.1XP_024302787.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  18. XM_024447011.1XP_024302779.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  19. XM_024447023.1XP_024302791.1  cyclin-D-binding Myb-like transcription factor 1 isoform X3

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:105438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  20. XM_024447013.1XP_024302781.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  21. XM_024447012.1XP_024302780.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  22. XM_017012865.2XP_016868354.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9Y222
    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  23. XM_017012872.2XP_016868361.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  24. XM_011516735.3XP_011515037.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    See identical proteins and their annotated locations for XP_011515037.1

    UniProtKB/Swiss-Prot
    Q9Y222
    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  25. XM_017012866.2XP_016868355.1  cyclin-D-binding Myb-like transcription factor 1 isoform X2

    Conserved Domains (4) summary
    smart00717
    Location:233289
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:297347
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:233288
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:187243
    Myb_DNA-bind_6; Myb-like DNA-binding domain
  26. XM_024447014.1XP_024302782.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  27. XM_017012878.2XP_016868367.1  cyclin-D-binding Myb-like transcription factor 1 isoform X7

    Conserved Domains (2) summary
    smart00717
    Location:70123
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  28. XM_024447015.1XP_024302783.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

    Conserved Domains (3) summary
    pfam00249
    Location:274329
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:228284
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:89438
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  29. XM_017012871.1XP_016868360.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  30. XM_017012875.1XP_016868364.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  31. XM_017012873.1XP_016868362.1  cyclin-D-binding Myb-like transcription factor 1 isoform X6

    UniProtKB/TrEMBL
    D6W5P0
    Conserved Domains (3) summary
    smart00717
    Location:864
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:72122
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:863
    Myb_DNA-binding; Myb-like DNA-binding domain
  32. XM_024447025.1XP_024302793.1  cyclin-D-binding Myb-like transcription factor 1 isoform X4

    Conserved Domains (3) summary
    pfam00249
    Location:215270
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:169225
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl28544
    Location:13379
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  33. XM_017012867.1XP_016868356.1  cyclin-D-binding Myb-like transcription factor 1 isoform X2

    Conserved Domains (4) summary
    smart00717
    Location:233289
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:297347
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam00249
    Location:233288
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam13921
    Location:187243
    Myb_DNA-bind_6; Myb-like DNA-binding domain

RNA

  1. XR_001744895.1 RNA Sequence

    Related
    ENST00000579850.5
  2. XR_002956500.1 RNA Sequence

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